AI Article Synopsis
- - This study investigated how low-temperature plasma jet using helium (LTP-helium) affects cariogenic biofilms made of different bacterial combinations, testing the treatment for various time durations (1, 3, 5, and 7 minutes)! - The effectiveness of LTP-helium was compared to a 0.12% chlorhexidine solution (positive control) and sterile physiologic solution (negative control), with significant reductions in biofilm viability observed with LTP-helium (p < 0.0001)! - Results showed LTP-helium significantly decreased the viability of multispecies biofilms, suggesting it could be a promising method for preventing and treating dental caries!
Article Abstract
This study aimed to determine the effects of low-temperature plasma jet produced in gas helium (LTP-helium) on cariogenic biofilms composedby and , and also by the combination of and . Biofilms were treated for 1, 3, 5, and 7 minutes. A 0.12% chlorhexidine solution was used as the positive control and sterile physiologic solution was the negative control. Biofilm viability was analyzed by viable cell recovery, scanning electron microscopy, and confocal laser scanning microscopy. All assays were performed intriplicate in three independent experiments. Multispecies biofilms exposed to LTP-helium had a significant reduction in viability when compared to the negative control (p < 0.0001). For biofilm formedby , and , LTP treatments for 5 and 7 minutes caused similar reduction of morethan 2 log. Also, a significant reduction in the viability of biofilms formedby , and was detected (p < 0.0001). In conclusion, LTP-helium reduced theviability of cariogenic biofilms with different microbial compositions, which indicates that LTP-helium is a potential tool for developing new protocols for dental caries prevention and treatment.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11391876 | PMC |
| http://dx.doi.org/10.1080/20002297.2024.2397831 | DOI Listing |
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