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Effects of dioscin from Dioscorea nipponica on TL1A/DR3 and Th9 cells in a collagen-induced arthritis mouse model.
Int Immunopharmacol
January 2025
Department of Anatomy, Basic Medical Institute, Chengde Medical University, Chengde 067000 Hebei, China. Electronic address:
Rheumatoid arthritis (RA) is a systemic autoimmune disease, and TL1A and its receptor DR3 play important roles in its pathogenesis. Th9 cells are involved in RA development. Dioscin from Dioscorea nipponica (DDN) has a therapeutic effect on RA, but its effect on TL1A/DR3 and Th9 cells remains unclear.
View Article and Find Full Text PDFEffects of Animal-Assisted Therapy for Anxiety Reduction in Children and Adolescents: A Systematic Review.
J Clin Med
January 2025
Institute of Psychology and Neuropsychology of Porto-IPNP Health, 4000-055 Porto, Portugal.
: Animal-Assisted Therapy (AAT) is a clinical approach aimed at building valuable human-animal relationships with both preventive and therapeutic goals. It is provided by a healthcare professional and involves animals (meeting certain criteria) as an integral part of the treatment process. This type of therapy has been shown to have multiple benefits in several areas, such as reducing anxiety in a variety of different groups of people.
View Article and Find Full Text PDFThe preventive effect of psychological and psychosocial interventions on postpartum depression: An overview of systematic reviews.
J Psychiatr Res
November 2024
Innovation Center of Humanistic Care and Health Management, School of Nursing, Hebei Medical University, Shijiazhuang, Hebei Province, China. Electronic address:
Background: Postpartum depression is a prevalent issue that significantly impacts the mental health of women, placing a substantial burden on individuals, families, and society. With the increasing evidence of postpartum depression prevention, conducting comprehensive assessments becomes essential to facilitate future clinical practices.
Methods: The systematic review and meta-analysis examined psychological and psychosocial interventions to prevent postpartum depression in perinatal women (antenatal and postnatal up to 12 months).
Guidance for an Effective Approach to Integrated Evidence Planning in a Dynamic World.
Clin Pharmacol Ther
January 2025
Boston Consulting Group, Zurich, Switzerland.
The value of a medicine is defined by its impact on patients, caregivers, health system, and society. A pharmaceutical company will generate evidence to demonstrate this value in various studies, including randomized clinical trials, non-interventional and observational studies, real-world data analyses, modeling, and simulation. The quality and strength of the evidence supporting a medicine's effectiveness, safety and product quality will drive decisions by healthcare system stakeholders for marketing authorization (regulatory authorities).
View Article and Find Full Text PDFHistoric cultural blocks are areas where a city's material cultural heritage and humanistic characteristics converge, showcasing the city's unique features and preserving rich and complete urban memories. Research on historic blocks primarily involves strategies related to protection, renewal, planning, and enhancement. However, there is a paucity of studies that explore the relationship between landscape value perception and tourist behavioral intentions from the perspective of recreation participants during the development and renewal of historic cultural blocks.
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