This paper presents a one-dimensional model that describes fluid flow in lymphangions, the segments of lymphatic vessels between valves, using quasilinear hyperbolic systems. The model incorporates a phenomenological pressure-cross-sectional area relationship based on existing literature. Numerical solutions of the differential equations align with known results, offering insights into lymphatic flow dynamics. This model enhances the understanding of lymph movement through the lymphatic system, driven by lymphangion contractions.
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http://dx.doi.org/10.1080/10255842.2024.2399769 | DOI Listing |
Comput Methods Biomech Biomed Engin
September 2024
Dipartimento di Matematica e Fisica "N. Tartaglia", Università Cattolica del Sacro Cuore, Brescia, Italy.
This paper presents a one-dimensional model that describes fluid flow in lymphangions, the segments of lymphatic vessels between valves, using quasilinear hyperbolic systems. The model incorporates a phenomenological pressure-cross-sectional area relationship based on existing literature. Numerical solutions of the differential equations align with known results, offering insights into lymphatic flow dynamics.
View Article and Find Full Text PDFMicromachines (Basel)
September 2023
Mechanical Engineering and Resource Sustainability Center (METRICS), University of Minho, 4800-058 Guimarães, Portugal.
A computational fluid dynamics (CFD) model of blood flow through hyperbolic contraction with a discrete phase model (DPM) was experimentally validated. For this purpose, the positions and velocities of red blood cells (RBCs) flowing in a microchannel with hyperbolic contraction were experimentally assessed using image analysis techniques, and were subsequently compared with the numerical results. The numerically and experimentally obtained velocity fields were in good agreement, with errors smaller than 10%.
View Article and Find Full Text PDFHeliyon
July 2022
Department of Chemical Engineering, Faculty of Engineering, University of Lagos, Akoka, Yaba, Lagos, Nigeria.
A numerical model for simulating and predicting blood flow dynamics in diseased arterial vessels has been developed. The time-dependent one-dimensional hyperbolic system of quasilinear partial differential equations which incorporates a diagnostic disease descriptor ( ) was used to simulate transient flow distribution for idealized healthy and diseased states. Blood flow simulations in the iliac arteries over about 125% of a cardiac cycle were generated and calibrated using the values from 0 to 3 representing hypothetical diseased states.
View Article and Find Full Text PDFEntropy (Basel)
October 2021
School of Mathematics, Sun Yat-sen University, Guangzhou 510275, China.
The main purpose of this review is to summarize the recent advances of the Conservation-Dissipation Formalism (CDF), a new way for constructing both thermodynamically compatible and mathematically stable and well-posed models for irreversible processes. The contents include but are not restricted to the CDF's physical motivations, mathematical foundations, formulations of several classical models in mathematical physics from master equations and Fokker-Planck equations to Boltzmann equations and quasi-linear Maxwell equations, as well as novel applications in the fields of non-Fourier heat conduction, non-Newtonian viscoelastic fluids, wave propagation/transportation in geophysics and neural science, soft matter physics, etc. Connections with other popular theories in the field of non-equilibrium thermodynamics are examined too.
View Article and Find Full Text PDFBull Math Biol
November 2021
Department of Mathematics and Applications, University of Naples "Federico II", Via Cintia 1, Monte S' Angelo, 80126, Naples, Italy.
A multiscale mathematical model is presented to describe de novo granulation, and the evolution of multispecies granular biofilms, in a continuously fed bioreactor. The granule is modelled as a spherical free boundary domain with radial symmetry. The equation governing the free boundary is derived from global mass balance considerations and takes into account the growth of sessile biomass as well as exchange fluxes with the bulk liquid.
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