Accelerated material development for refractory ceramics triggers possibilities in context to enhanced energy efficiency for industrial processes. Here, the gathering of comprehensive material data is essential. High temperature-confocal laser scanning microscopy (HT-CLSM) displays a highly suitable in-situ method to study the underlying dissolution kinetics in the slag over time. A major drawback concerns the efficient and accurate processing of the collected image data. Here, we introduce an attention encoder-decoder convolutional neural network enabling the fully automated evaluation of the particle dissolution rate with a precision of 99.1%. The presented approach provides accurate and efficient analysis capabilities with high statistical gain and is highly resilient to image quality changes. The prediction model allows an automated diameter evaluation of the MgO particles' dissolution in the silicate slag for different temperature settings and various HT-CLSM data sets. Moreover, it is not limited to HT-CLSM image data and can be applied to various domains.
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http://dx.doi.org/10.1038/s41598-024-71640-8 | DOI Listing |
J Colloid Interface Sci
January 2025
University of Zagreb, Faculty of Science, Department of Chemistry, Zagreb, HR-10000, Croatia.
The phenomenon of solid dissolution into a solution constitutes a fundamental aspect in both natural and industrial contexts. Nevertheless, its intricate nature at the microscale poses a significant challenge for precise quantitative characterization at a foundational level. In this work, the influence across three specific cleavage planes, namely (100), (111), and (110) on the dissolution kinetics of fluorite in aqueous environments was examined from both experimental and theoretical standpoints.
View Article and Find Full Text PDFInt J Pharm
January 2025
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario M5S 3M2, Canada. Electronic address:
The objective of this study is to address the unanswered question whether sustained supersaturation generated from amorphous solid dispersions (ASDs) formulated in insoluble hydrogel carriers will result in better bioavailability over that of spring-and-parachute type of dissolution profiles of ASDs formulated in water-soluble carriers. This was achieved by investigating the effects of supersaturation generation rates and doses on the extent of absorption (i.e.
View Article and Find Full Text PDFSmall Methods
January 2025
School of Physical Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Electrochemical lithium extraction from salt lakes using LiMnO (LMO) presents an eco-friendly, highly controllable, and efficient method. However, its practical application is limited due to its structure instability and manganese dissolution in water. Herein, a high-performance LMO coated with ≈3.
View Article and Find Full Text PDFSmall
January 2025
Key Lab of Bamboo and Rattan Science & Technology, International Center for Bamboo and Rattan, Beijing, 100102, P. R. China.
A nitrogen-coordinated Fe single-atom catalyst (SA Fe-N/C) is synthesized using a homogeneous ethanol-based dissolution system with bamboo kraft lignin serving as the carbon source. Uniformly dispersed Fe atoms with an interatomic distance of less than 2 Å throughout the SA Fe-N/C structure are revealed through X-ray absorption spectral analysis and HAADF-STEM images, which possessed a high Fe loading of 2.69%.
View Article and Find Full Text PDFAAPS PharmSciTech
January 2025
Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Assiut University, Assiut, Egypt.
The present work focuses on the production of sildenafil co-evaporates loaded emulgels as topical dosage forms for the treatment of premature ejaculation and erectile dysfunction. Topical administration of sildenafil citrate (SILD) co-evaporates is expected to improve the bioavailability profile of the drug and to avoid the severe side effects accompanying the traditional SILD dosage forms, especially for prohibited cardiovascular cases. Firstly, the solubility of SILD was improved via solid dispersion via co-evaporation technique using PEG-5KDa and PVP-K90 as hydrophilic carriers.
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