AI Article Synopsis
- The study aimed to assess how effective new diffusion-weighted imaging (DWI) findings are in diagnosing placenta accreta spectrum (PAS) in pregnant women.
- Researchers analyzed MRI results from 49 women, identifying features such as diffusion lacunae, which are unique patterns that can indicate PAS.
- Results showed significant differences in the number and size of these diffusion lacunae between patients with PAS and those without, suggesting that these DWI features, along with flow voids, can improve the accuracy of diagnosing PAS.
Article Abstract
Objective: To evaluate the usefulness of novel diffusion-weighted imaging (DWI) findings for diagnosing placenta accreta spectrum (PAS).
Materials And Methods: This retrospective study included 49 pregnant women with suspected PAS who underwent 1.5 T placental MRI. Diffusion lacunae were defined as intraplacental areas showing hypointensity on DWI and hyperintensity on the apparent diffusion coefficient map. Two radiologists evaluated the number and size of placental lacunae on DWI, and flow void in the diffusion lacunae on T2-weighted imaging. The radiologists also evaluated established MRI features of PAS described in the SAR-ESUR consensus statement. Pearson's chi-square test or Mann-Whitney U test was used to compare findings between patients with and without PAS. Interobserver reliability for DWI and established MRI features was also assessed. Optimal thresholds for the number and maximum size of diffusion lacunae for differentiating PAS from the no-PAS group were determined using receiver operating characteristic curve analyses.
Results: Eighteen patients were diagnosed with PAS, and 31 patients with placental previa without PAS. The number and maximum size of diffusion lacunae were significantly larger in patients with than in patients without PAS (p < 0.0001). Combining assessment of the number of diffusion lacunae with assessment of their maximum size yielded a diagnostic performance with sensitivity, specificity and accuracy of 83%, 94% and 90%, respectively. Flow voids within the diffusion lacunae had sensitivity, specificity and accuracy of 88%, 84% and 86%, respectively.
Conclusion: The number and size of diffusion lacunae, and T2 flow void in diffusion lacunae may be useful findings for diagnosing PAS.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11604-024-01657-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association of glymphatic clearance function with imaging markers and risk factors of cerebral small vessel disease.
J Stroke Cerebrovasc Dis
December 2024
Department of Radiology, Zigong First People's Hospital, Zigong, PR China. Electronic address:
Background: Cerebral small vessel disease (CSVD) is a common disease in the elderly, and its pathogenesis is still being explored. Glymphatic clearance function can be evaluated by diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) index. This study aims to investigate the changes in glymphatic clearance function in CSVD patients and its relationship with imaging markers and risk factors of CSVD.
View Article and Find Full Text PDFUnique bone histology of modern giant salamanders: a study on humeri and femora of Andrias spp.
Zoological Lett
October 2024
Department of Biosphere-Geosphere Science, Okayama University of Science, Ridai-Cho 1-1, Kita-Ku, Okayama, 700005, Japan.
The osteohistology of Andrias spp. is a pivotal analogue for large fossil non-amniotes (e.g.
View Article and Find Full Text PDFQuantitative structure permeability relationships for phenolic compounds applied to human epidermal membranes in various solvents.
Eur J Pharm Sci
January 2025
Therapeutics Research Centre, Frazer Institute, University of Queensland, Brisbane, Australia.
Purpose: This study examined how solvent-skin-solute interactions influenced the human epidermal permeation of three similar-sized phenolic compounds applied in a series of different solvents.
Methods: Human epidermal permeation fluxes and lag times of three phenolic compounds were assessed in Franz cells for a range of solvents varying in molecular size and solubility parameters. In order to develop a mechanistic understanding of the determinants of the permeation findings, the solubility of the compounds in solvents and stratum corneum, the extent of solvent uptake by the stratum corneum and the impact of the solvents on skin hydration and transepidermal water loss were also measured.
Diffusion lacunae: a novel MR imaging finding on diffusion-weighted imaging for diagnosing placenta accreta spectrum.
Jpn J Radiol
September 2024
Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, Japan.
Article Synopsis
- The study aimed to assess how effective new diffusion-weighted imaging (DWI) findings are in diagnosing placenta accreta spectrum (PAS) in pregnant women.
- Researchers analyzed MRI results from 49 women, identifying features such as diffusion lacunae, which are unique patterns that can indicate PAS.
- Results showed significant differences in the number and size of these diffusion lacunae between patients with PAS and those without, suggesting that these DWI features, along with flow voids, can improve the accuracy of diagnosing PAS.
Pure argyrophilic grain disease revisited: independent effects on limbic, neocortical, and striato-pallido-nigral degeneration and the development of dementia in a series with a low to moderate Braak stage.
Acta Neuropathol Commun
July 2024
Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama, 700-8558, Japan.
Article Synopsis
- Agyrophilic grains (AGs) are brain lesions that accumulate four-repeat tau and are linked to age-related cognitive decline, but their role in dementia remains uncertain due to conflicting research.
- A study analyzed 30 cases of pure argyrophilic grain disease (pAGD) and 34 control cases to assess the quantity and distribution of Gallyas-positive AGs and associated neuronal loss in various brain regions.
- Results indicated that higher concentrations of AGs in the amygdala and hippocampus significantly correlated with neuronal loss and affected dementia independently of other factors like age and other neurodegenerative stages.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!