With the rapid growth of the gig economy in China, millions of food delivery e-bikers are making their living by rushing on the street. Speeding is one of their most common risky riding behaviours, leading to severe traffic crashes. Based on 2-month naturalistic cycling data of 46 full-time food delivery e-bikers in Changsha, their speeding behaviour is deeply studied with the individual daily speeding proportion being taken as the speeding indicator. A beta regression model is built to identify the factors significantly influencing the indicator. The estimation results reveal that female riders, middle-aged riders and riders with a bachelor's degree are less likely to engage in speeding. The same result is indicated for those working longer or experiencing more crashes. Additionally, holidays and riding distance are found to have significantly positive influences. Finally, some countermeasures are proposed to prevent speeding among food delivery e-bikers.
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http://dx.doi.org/10.1080/10803548.2024.2393027 | DOI Listing |
Prosthet Orthot Int
January 2025
Ida Orthopedics, Istanbul, Turkey.
A boy with bilateral congenital anomalies of the upper extremities with transverse absence of the left arm (agenesis) and absence of right thumb (disgenesis), fixed elbow in extension due to humeroradial synostosis thought that the humerus was intact. His wrist could move passively with 50° flexion, 0° extension, and 70° radial deviation. The other 4 fingers were intact, 4-5 metatarsal bones were in synostosis, and the fifth finger was clinodactyly.
View Article and Find Full Text PDFInflammation
January 2025
Research Center for Food and Cosmetic Safety and Center for Drug Research and Development, Chang Gung University of Science and Technology, Kweishan, Taoyuan, Taiwan.
Atopic dermatitis (AD) is a multifaceted inflammatory skin condition characterized by the involvement of various cell types, such as keratinocytes, macrophages, neutrophils, and mast cells. Research indicates that flavonoids possess anti-inflammatory properties that may be beneficial in the management of AD. However, the investigation of the glycoside forms for anti-AD therapy is limited.
View Article and Find Full Text PDFActa Pharm Sin B
December 2024
Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
The respiratory tract is susceptible to various infections and can be affected by many serious diseases. Vaccination is one of the most promising ways that prevent infectious diseases and treatment of some diseases such as malignancy. Direct delivery of vaccines to the respiratory tract could mimic the natural process of infection and shorten the delivery path, therefore unique mucosal immunity at the first line might be induced and the efficiency of delivery can be high.
View Article and Find Full Text PDFActa Pharm Sin B
December 2024
Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, West China School of Pharmacy, Mental Health Center and National Chengdu Center for Safety Evaluation of Drugs, West China Hospital, Sichuan University, Chengdu 610041, China.
The neurovascular unit (NVU) is highly responsible for cerebral homeostasis and its dysfunction emerges as a critical contributor to Alzheimer's disease (AD) pathology. Hence, rescuing NVU dysfunction might be a viable approach to AD treatments. Here, we fabricated a self-regulated muti-functional nano-modulator (siR/PIO@RP) that can intelligently navigate to damaged blood-brain barrier and release therapeutical cargoes for synergetic AD therapy.
View Article and Find Full Text PDFRSC Adv
January 2025
Tianjin Key Laboratory for Modern Drug Delivery and High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University Weijin Road Tianjin 300072 China +86-22-87401895 +86-22-87401895.
[This retracts the article DOI: 10.1039/C8RA07163B.].
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