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Case Report: AMSAN variant of GBS complicating immediate postpartum period with severe dysautonomia leading to Posterior Reversible Encephalopathy Syndrome. | LitMetric

AI Article Synopsis

  • A 20-year-old woman experienced a spontaneous loss of her fetus at 30 weeks and developed sudden paralysis and breathing issues 8 days later, starting from her legs and progressing upwards.
  • She was diagnosed with Guillain Barré Syndrome (GBS) and underwent plasma exchange treatment.
  • After developing complications like high blood pressure and seizures, she was diagnosed with Posterior Reversible Encephalopathy Syndrome (PRES), but with treatment, she regained her vision and made a good recovery.

Article Abstract

A 20's primiparous woman, following spontaneous expulsion of intrauterine death of the fetus at 30 weeks of gestation, presented on post-partum day 8 with acute onset flaccid quadriparesis and breathing difficulty, which had rapidly progressed to involve the legs on day 3 up to her upper limbs on post-partum day 5. Following examination, Guillain Barre Syndrome (GBS) with ascending diaphragmatic involvement was diagnosed, and plasma exchange was initiated. She developed raised blood pressure, headache, sudden onset visual loss with 2 episodes of generalized seizures on post-partum day 14. Brain MRI and clinical suspicion helped diagnose Posterior Reversible Encephalopathy Syndrome (PRES). The patient was treated with anticonvulsants and antihypertensive agents. She regained her vision over the next two days, completed the treatment for GBS, and made a good recovery with independence for advanced activities of daily living on follow-up.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384208PMC
http://dx.doi.org/10.12688/f1000research.147190.2DOI Listing

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