Modifiable lifestyle factors evidence great promise in reducing cognitive decline in older adults. Greater consumption to the MIND diet (Morris et al.) and increased daily physical activity (Buchman et al.) are associated with higher cognitive functioning. The interactive effects of lifestyle factors on cognition in older adults has not been investigated extensively. The present study examined the interaction between MIND diet consumption and intensity of physical activity on cognition in community-dwelling older adults. The sample included 215 older adults (159 female, 79.8; =15.5) from the Memory and Aging Project (Bennet et al.). The measures included the food frequency questionnaire (FFQ, MIND diet consumption), a portable actigraph worn 24 h a day for ten days (activity intensity), and a neuropsychological battery (cognitive variables). Controlling for age and education, multiple regression analyses revealed that MIND diet consumption significantly predicted global cognition (< .05). Physical activity significantly predicted global cognition (< .05), and processing speed (< .01). Interaction effects were significant in global cognition (< .05), and episodic memory (< .01) revealing a pattern that those with the lowest MIND diet consumption may experience greater cognitive benefits from physical activity in than those with higher diet consumption. Findings suggest that older adults who do not consume the MIND diet closely may experience greater benefit in cognitive functioning from exercise than individuals who more greatly consume the diet.
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http://dx.doi.org/10.1080/13854046.2024.2399866 | DOI Listing |
Alzheimers Dement
December 2024
Institute for Memory Impairments and Neurological Disorders (MIND), Irvine, CA, USA.
Background: Late-onset Alzheimer's disease (LOAD) represents the majority of human AD cases, yet the availability of animal models that accurately reflect LOAD progression and pathology is limited. Traditional transgenic mouse models including 3xTg-AD and 5xFAD rely on supraphysiological overexpression of familial AD risk genes, failing to adequately replicate the disease progression observed in LOAD. Here, we present the first characterization of MODEL-AD1 (MAD1), a platform mouse developed by the Model Organism Development and Evaluation for Late-onset Alzheimer's Disease (MODEL-AD) Consortium.
View Article and Find Full Text PDFChronobiol Int
January 2025
Department of Nutrition and Dietetics, Firat University, Elazig, Turkey.
The effects of chronotype and diet on obese individuals have been reported in previous studies. This study aimed to examine the relationship between the Mediterranean-DASH intervention for neurodegenerative delay (MIND) diet, chronotype and lifestyle factors in different types of overweight and obese people. 1100 obese individuals participated in this cross-sectional study.
View Article and Find Full Text PDFSci Rep
December 2024
Faculty of Humanities and Social Sciences,Institute of Psychology, University of Pécs, 6 Ifjúság Street, Pécs, 7624, Hungary.
Living with chronic conditions like diabetes mellitus (DM) or insulin resistance (IR) requires significant self-management, adding to daily life stressors. This stress, known as diabetes distress, along with health empowerment from proper diet and lifestyle, and motivation to eat healthily, greatly impacts quality of life and disease outcomes. Different patient subgroups (type 1 diabetic (T1DM), type 2 diabetic (T2DM), and insulin resistant (IR) individuals) face these challenges differently.
View Article and Find Full Text PDFJ Anim Sci
December 2024
Centre for Animal Nutrition and Welfare, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210 Vienna, Austria.
We recently reported factors leading to different severity of ruminal pH drop in primiparous cows fed the same diet during transition and early lactation. The present study evaluates the effects of those severities on performance and several blood and balance parameters in the same 24 primiparous cows from 3 wk before calving until wk 10 in lactation. Dietary concentrate was increased for all cows from 32 before calving to 60% (DM basis) over the first wk in lactation, resulting in a diet with 40% non-fiber carbohydrates (NFC), and 14.
View Article and Find Full Text PDFIntern Med J
December 2024
Department of Paediatrics, Fiona Stanley Hospital, Perth, Western Australia, Australia.
Background: The frequency of EoE has been increasing in Northern Hemisphere cohorts, yet there is a scarcity of data in our region. Regional climatic factors, and lifestyle habits may influence the presentation of EoE, and appropriate management is crucial to prevent complications. WIth this is mind we undertook the first comprehensive multisite study of EoE in Australasian children.
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