AI Article Synopsis
- Neurodegenerative diseases pose a significant challenge to our aging population, with current treatments primarily focused on relieving symptoms rather than addressing underlying causes.
- New developments in active immunotherapy show promise by helping the immune system create antibodies that target harmful misfolded amyloid proteins associated with these diseases.
- The text reviews ongoing clinical trials and successful vaccines designed for treating Alzheimer's and Parkinson's diseases, showcasing advances in this area of research.
Article Abstract
Neurodegenerative diseases strongly impact our aging society, with treatments providing only symptomatic relief. Recent advancements in active immunotherapy offer solutions by stimulating the immune system to produce antibodies against misfolded and toxic amyloid proteins. We discuss vaccines under clinical evaluation for Alzheimer's and Parkinson's diseases, highlighting successes and ongoing trials.
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| http://dx.doi.org/10.1016/j.molmed.2024.08.005 | DOI Listing |
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