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Integrating hot topics and implementation of treatable traits in asthma. | LitMetric

Integrating hot topics and implementation of treatable traits in asthma.

Eur Respir J

Centre of Excellence in Treatable Traits, College of Health, Medicine and Wellbeing, The University of Newcastle, New Lambton Heights, Australia.

Published: December 2024

AI Article Synopsis

  • Asthma presents various symptoms and issues that vary between patients, making it a complex condition that requires a tailored management strategy.
  • The Treatable Traits model of care focuses on identifying specific traits in various areas, like pulmonary health and comorbidities, which can be effectively treated using evidence-based therapies.
  • This model encourages collaboration between clinicians and patients to create personalized management plans, leading to better asthma control and improved quality of life, with potential applications in other health conditions as well.

Article Abstract

People with asthma experience many different problems related to their illness. The number and type of problems differ between patients. This results in asthma being a complex and heterogeneous disorder which mandates a personalised approach to management. These features pose very significant challenges for the effective implementation of evidence-based management. "Treatable traits" is a model of care that has been specifically designed to address these issues. Traits are identified in the pulmonary, extrapulmonary (comorbidity) and behavioural/risk factor domains. Traits are clinically relevant, recognisable with validated trait identification markers and treatable using evidence-based therapies. The clinician and patient agree on a personalised management plan that addresses the relevant traits, and trials show superiority of this approach with significant improvements in asthma control and quality of life. A number of tools have now been developed to assist the clinician in the implementation of this approach. The success of the treatable traits model of care is now being realised in other disease areas.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11618818PMC
http://dx.doi.org/10.1183/13993003.00861-2024DOI Listing

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