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Epigenetic reprogramming enables NF1A/B oncogenic role in SHH medulloblastoma. | LitMetric
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Epigenetic reprogramming enables NF1A/B oncogenic role in SHH medulloblastoma.

Sara Badodi Silvia Marino

Dev Cell

Brain Tumour Research Centre, Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK; Barts Brain Tumour Centre, Faculty of Medicine and Dentistry, Queen Mary University of London and Barts Health NHS Trust, London, UK. Electronic address:

Published: September 2024

In this issue of Developmental Cell, Shiraishi et al. investigate the epigenetic changes occurring during the formation of SHH medulloblastoma and show that an epigenomic shift renders Nuclear Factor I family of transcription factors oncogenic.

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 Source
http://dx.doi.org/10.1016/j.devcel.2024.07.002DOI Listing

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