Male infertility and obesity.

Curr Opin Endocrinol Diabetes Obes

Division of Endocrinology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, California, USA.

Published: December 2024

AI Article Synopsis

  • Obesity is negatively affecting male reproductive health, contributing to infertility issues.
  • Research is exploring the harmful effects of reactive oxygen species and the impact of when obesity starts on male reproduction.
  • The review discusses various mechanisms, such as metabolic issues and hormonal changes, that link obesity to reproductive problems, and suggests new management strategies to enhance men's reproductive health.

Article Abstract

Purpose Of Review: The increasing rate of obesity is having an adverse impact on male reproduction.

Recent Findings: The negative effect of reactive oxygen species on male reproductive tissues and the age of onset of obesity are new areas of research on male infertility.

Summary: This review highlights how obesity impairs male reproduction through complex mechanisms, including metabolic syndrome, lipotoxicity, sexual dysfunction, hormonal and adipokine alterations as well as epigenetic changes, and how new management strategies may improve the reproductive health of men throughout life.

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Source
http://dx.doi.org/10.1097/MED.0000000000000883DOI Listing

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