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Advances in the use of chlorhexidine for periodontitis treatment in diabetic patients: A review. | LitMetric

Advances in the use of chlorhexidine for periodontitis treatment in diabetic patients: A review.

Medicine (Baltimore)

Key Laboratory of Emergency and Trauma of Ministry of Education, Department of Stomatology, Key Laboratory of Hainan Trauma and Disaster Rescue, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, China.

Published: September 2024

AI Article Synopsis

  • Periodontitis and diabetes mellitus have a two-way relationship, affecting each other's severity and management.
  • This review discusses the use of chlorhexidine in treating periodontal issues in diabetic patients, noting its effectiveness against bacteria and plaque but questioning its effects on blood sugar control.
  • The article highlights the lack of research on chlorhexidine's role in gestational diabetes and calls for collaborative efforts between dental and medical professionals to improve care for diabetic patients with periodontitis.

Article Abstract

Periodontitis and diabetes mellitus exhibit a bidirectional relationship. This narrative review descriptively outlines the role of chlorhexidine in the periodontal treatment of diabetic patients, focusing on its antimicrobial mechanisms against microbial communities and its antiplaque effects. Although chlorhexidine is proven to be effective in combating microbial presence and improving gingivitis with substantial supporting evidence, its impact on glycemic control and insulin resistance in diabetic patients remains contentious. Additionally, the effectiveness of chlorhexidine as an adjunctive chemotherapeutic in the periodontal treatment of gestational diabetes has not yet been studied, highlighting a gap in research that necessitates further prospective studies and randomized controlled trials. Considering the interconnection between periodontal inflammation and glycemic levels, this article finally advocates for collaborative care between dental and medical professionals to manage periodontitis in diabetic patients effectively.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11383263PMC
http://dx.doi.org/10.1097/MD.0000000000039627DOI Listing

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