Measurement of computed tomography modulation transfer function with a novel polymethyl methacrylate phantom.

Phys Eng Sci Med

X-ray Safety Australia, Ashgrove West, PO Box 574, Ashgrove West, QLD, 4060, Australia.

Published: December 2024

A novel phantom for measuring the 10% and 50% values of the modulation transfer function (MTF) for computed tomography scanners (CT) was investigated. The phantom was constructed by drilling rows of holes of different sizes and frequencies into a small block of polymethyl methacrylate (PMMA). The MTF at a given frequency was determined from the ratio of the range of Hounsfield units within the rows of holes at different frequencies, and the difference in Hounsfield units between air and PMMA. A MTF curve was plotted from measurements at different frequencies and the 10% and 50% MTF values were obtained from a cubic spline interpolation. The MTF results obtained with the drilled hole phantom method were compared to a conventional method - using a thin wire and Spice-CT ImageJ Plugin- and with identical acquisition and reconstruction parameters. The drilled hole phantom measured the 50% MTF with reasonable accuracy but underestimated the 10% MTF by 8.2% on average. MTF measurements were reproducible for repeated image acquisitions and with different users analysing the images, and the phantom was able to accurately measure the change in MTF when measured on images using different reconstruction kernels. The tool may find application as a cheap, easy to use method for routine QC testing of CT scanners.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13246-024-01468-zDOI Listing

Publication Analysis

Top Keywords

mtf
9
computed tomography
8
modulation transfer
8
transfer function
8
polymethyl methacrylate
8
10% 50%
8
rows holes
8
pmma mtf
8
hounsfield units
8
50% mtf
8

Similar Publications

Reconstructive techniques for chest and breast deformities in Poland syndrome: An up-to-date systematic review.

J Plast Reconstr Aesthet Surg

December 2024

Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University, Stanford, CA, United States.

Background: Poland syndrome (PS) is a congenital abnormality defined as aplasia or hypoplasia of the unilateral pectoralis muscle and breast tissue that may be accompanied by limb or thoracic deformities. Reconstruction of deformities associated with PS is challenging owing to the spectrum of differences. We aimed to evaluate the trends in surgical management of chest and breast anatomical anomalies associated with PS.

View Article and Find Full Text PDF

Deep learning model to diagnose cardiac amyloidosis from haematoxylin/eosin-stained myocardial tissue.

Eur Heart J Imaging Methods Pract

January 2025

Department of Cardiovascular Medicine, Faculty of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

Aims: Amyloid deposition in myocardial tissue is a definitive feature for diagnosing cardiac amyloidosis, though less invasive imaging modalities such as bone tracer cardiac scintigraphy and cardiac magnetic resonance imaging have been established as first steps for its diagnosis. This study aimed to develop a deep learning model to support the diagnosis of cardiac amyloidosis from haematoxylin/eosin (HE)-stained myocardial tissue.

Methods And Results: This single-centre retrospective observational study enrolled 166 patients who underwent myocardial biopsies between 2008 and 2022, including 76 patients diagnosed with cardiac amyloidosis and 90 with other diagnoses.

View Article and Find Full Text PDF

Purpose: To evaluate image quality (IQ) of for-processing (raw) and for-presentation (clinical) radiography images, under different exposure conditions and digital image post-processing algorithms, using a phantom that enables multiple detection tasks.

Methods: A modified version of the radiography phantom described in the IAEA Human Health Series No. 39 publication was constructed, incorporating six additional Aluminum (Al) targets of thicknesses both smaller and larger than the standard one.

View Article and Find Full Text PDF

Zinc is an essential trace element. The regulatory mechanism of zinc and its transporters in fetal growth in monochorionic diamniotic (MCDA) twins with selective intrauterine growth restriction (MCDA-sIUGR) is unclear. A total of 45 MCDA twins were divided into two groups, MCDA (n=37) and MCDA-sIUGR (n=8), to investigate their possible effects on fetal growth.

View Article and Find Full Text PDF

A Comparative Analysis of the Effects of Misaligning Different Trifocal Intraocular Lenses.

J Clin Med

December 2024

The David J Apple Center for Vision Research, Department of Ophthalmology, Heidelberg University Eye Clinic, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.

This laboratory study aims to assess the effects of misaligning different trifocal intraocular lenses (IOLs) under varying spectral and corneal spherical aberration (SA) conditions. With an IOL metrology device under monochromatic and polychromatic conditions, the following models were studied: AT ELANA 841P, AT LISA Tri 839MP, FineVision HP POD F, Acrysof IQ PanOptix, and Tecnis Synergy ZFR00V. The SA was simulated using an aberration-free and average-SA cornea.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!