Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14787210.2024.2403021 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Engineering of -Based Tryptophan Biosensors for Dynamic Control of Violacein Production.
J Agric Food Chem
November 2024
College of Agronomy and Biotechnology, Southwest University, Chongqing 400715, China.
Tryptophan not only serves as a fundamental building block for protein synthesis but also acts as a metabolic precursor for a diverse array of high-value chemicals. Although a few tryptophan-responsive biosensors are currently available, there is a growing interest in developing high-performance biosensors. In this study, we create a miniature toolkit of tryptophan biosensors based upon the leader regulatory region of the operon, which is responsible for tryptophan catabolism in .
View Article and Find Full Text PDFUse of Bacterial Toxin-Antitoxin Systems as Biotechnological Tools in Plants.
Int J Mol Sci
September 2024
Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain.
Toxin-antitoxin (TA) systems in bacteria are key regulators of the cell cycle and can activate a death response under stress conditions. Like other bacterial elements, TA modules have been widely exploited for biotechnological purposes in diverse applications, such as molecular cloning and anti-cancer therapies. However, their use in plants has been limited, leaving room for the development of new approaches.
View Article and Find Full Text PDFLong Dynamic β1-β2 Loops in MazF Toxins Affect the Interaction Modes and Strengths of the Toxin-Antitoxin Pairs.
Int J Mol Sci
September 2024
MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China.
Tuberculosis is a worldwide plague caused by the pathogen (). Toxin-antitoxin (TA) systems are genetic elements abundantly present in prokaryotic organisms and regulate important cellular processes. MazEF is a TA system implicated in the formation of "persisters cells" of , which contain more than 10 such members.
View Article and Find Full Text PDFMethicillin resistant Staphylococcus aureus mazEF expression promotes infections by influencing cellular growth, antibiotic sensitivity, and formation of biofilms.
Sci Rep
September 2024
Arthritis and Arthroplasty Design Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Staphylococcus aureus infections are hard to treat due to the emergence of antibiotic resistant strains, as well as their ability to form biofilms. The MazEF toxin-antitoxin system is thought play a role in bacterial biofilm phenotype as well as antibiotic resistance. In S.
View Article and Find Full Text PDFMazEF toxin-antitoxin systems: their role in stress response and drug resistance.
Expert Rev Anti Infect Ther
November 2024
Microbiology Department, Faculty of Allied Health Sciences, Sri Guru Gobind Singh, Tricentenary University, Gurugram, India.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!