Introduction: Drug-related problems (DRPs) are treatment-related occurrences that affect therapeutic efficacy. In a previous study, approximately 279 out of 330 (84.5%) patients with type 2 diabetes mellitus (T2DM) had experienced at least one DRP, including non-optimal drug effects ( = 240, 52.7%) and indications without medication ( 137, 30.1%). Patients who were hospitalised for 5-10 days had the highest number of DRPs. Therefore, this study investigates the association between DRPs and length of stay (LoS) in patients with T2DM.
Methods: A cross-sectional study was conducted from January 2020 to May 2023 at Rumah Sakit Akademik, Universitas Gadjah Mada, Yogyakarta, Indonesia. Clinical pharmacists reviewed electronic health data to examine DRPs. The Fisher's exact test evaluated the association between DRPs and LoS.
Results: A total of 60.7% ( = 17) of the participants were females, with the majority falling into the age group ≥ 65 years old ( = 11, 29.7%). A significant portion experienced LoS > 7 days ( = 17, 60.7%). Antidiabetic monotherapy was predominant, and the categories of DRPs included adverse drug reaction ( 15, 40.5%), dosage too high ( = 6, 16.2%), wrong drug ( = 6, 16.2%), non-adherence ( = 4, 10.8%), need for additional therapy ( 4, 10.8%) and dosage too low ( 2, 5.4%). A significant association was observed between non-adherence and LoS ( 0.016). The possibility of experiencing LoS of 1-7 days increased by 3.43 times with improved non-adherence (OR = 3.43; 95% CI: 1.83, 6.39). In this context, non-adherence refers to DRPs associated with the non-compliance of patients with the prescribed treatment plan.
Conclusion: This study concludes that non-adherence was significantly associated with hospital LoS.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377014 | PMC |
http://dx.doi.org/10.21315/mjms2024.31.4.13 | DOI Listing |
J Am Med Dir Assoc
January 2025
School of Pharmacy and Pharmacology, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.
Objectives: To investigate the rate of, and factors affecting, acceptance of pharmacists' recommendations by medical prescribers following medication reviews conducted in non-hospitalized older adults.
Design: A systematic review and meta-analysis with meta-regression.
Setting And Participants: Older adults (mean age ≥55 years) residing in the community or in aged care facilities (ie, non-hospitalized) who had received an individualized medication review by a pharmacist.
Scand J Prim Health Care
January 2025
Center for General Practice, Aalborg University, Aalborg, Denmark.
Introduction: Polypharmacy is widespread. The demographic shift toward older patients receiving multiple medications increases risk and drug-related problems in these patients.
Objective: To investigate patient perspectives on polypharmacy and the experienced effects of medication reviews by pharmacists in general practice.
Ann Pharm Fr
January 2025
Unité de pharmacie clinique et thérapeutique, UFR sciences pharmaceutiques et biologiques, Université Felix Houphouët-Boigny, Abidjan, Côte d'Ivoire.
Objective: Our aim was to analyze pharmaceutical interventions related to heart failure (HF) outpatient treatment.
Methods: An observationnal study was carried out over 6 months at the Abidjan Institute of Cardiology (ICA). Data were collected using a survey form that focused on, therapeutic adherence, drugs related-problems (DRP) and pharmaceutical interventions (PI).
Int J Clin Pharm
January 2025
Department of Clinical Pharmacy, Leopold-Franzens Universität, Innsbruck, Austria.
Background: Drug-related problems (DRPs) are significant issues in healthcare contributing to adverse health outcomes and increased healthcare costs. While community pharmacists play a pivotal role in identifying, classifying, and documenting DRPs, there is a need to map approaches undertaken.
Aim: The aim of this scoping review was to examine the approaches to identifying, classifying, and documenting DRPs in community pharmacies in Europe, and their associated barriers and facilitators.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!