Orbital defects due to congenital causes, cancer, and trauma can compromise appearance and function, creating a deep psychological impact on an individual's life. The prosthetic rehabilitation of such patients is challenging. The objective of prosthetic treatment of an ocular defect is to provide a well-fitting ocular prosthesis that closely resembles the original eye, restoring the patient's self-confidence and social acceptance. Ocular prostheses can be customized or prefabricated. The challenge encountered with prefabricated eye prostheses is a poor fit. Customized prostheses exhibit better fit, aesthetic outcome, and comfort to the patient in the long term. The article describes a technique to fabricate an ocular prosthesis with a stock iris and customized sclera that is both functional and aesthetically pleasing.
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http://dx.doi.org/10.7759/cureus.66457 | DOI Listing |
Nat Commun
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Study Center for Ocular Diseases, Guangzhou, China.
Photoreceptors are specialized neurons at the core of the retina's functionality, with optical accessibility and exceptional sensitivity to systemic metabolic stresses. Here we show the ability of risk-free, in vivo photoreceptor assessment as a window into systemic health and identify shared metabolic underpinnings of photoreceptor degeneration and multisystem health outcomes. A thinner photoreceptor layer thickness is significantly associated with an increased risk of future mortality and 13 multisystem diseases, while systematic analyses of circulating metabolomics enable the identification of 109 photoreceptor-related metabolites, which in turn elevate or reduce the risk of these health outcomes.
View Article and Find Full Text PDFOphthalmologie
January 2025
Augenklinik Sulzbach, Knappschaftsklinikum Saar, An der Klinik 10, 66280, Sulzbach/Saar, Deutschland.
Background: The increasing bureaucratic burden in everyday clinical practice impairs doctor-patient communication (DPC). Effective use of digital technologies, such as automated semantic speech recognition (ASR) with automated extraction of diagnostically relevant information can provide a solution.
Objective: The aim was to determine the extent to which ASR in conjunction with semantic information extraction for automated documentation of the doctor-patient dialogue (ADAPI) can be integrated into everyday clinical practice using the IVI routine as an example and whether patient care can be improved through process optimization.
Rev Med Suisse
January 2025
Service d'ophtalmologie, Hôpitaux universitaires de Genève, 1211 Genève 14.
Ophthalmology is notable for significant technological innovations (e.g laser, microscopy…) that allow for diagnostic and therapeutic advances every year. This article presents the main significant therapeutic progress and highlights the growing use of artificial intelligence in diagnosis of eye disease.
View Article and Find Full Text PDFiScience
January 2025
School of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran 14399-57131, Iran.
Microsaccades, a form of fixational eye movements, help maintain visual stability during stationary observations. This study examines the modulation of microsaccadic rates by various stimulus categories in monkeys and humans during a passive viewing task. Stimulus sets were grouped into four primary categories: human, animal, natural, and man-made.
View Article and Find Full Text PDFOphthalmol Sci
November 2024
Notal Vision Inc., Manassas, Virginia.
Purpose: To validate the performance of the Notal OCT Analyzer (NOA) in processing self-administered OCT images from an OCT system designed for home use (home OCT [HOCT]) as part of a pivotal study aimed at achieving de novo United States Food and Drug Admininstration marketing authorization.
Design: A prospective quantitative cross-sectional artificial intelligence study.
Participants: The study enrolled adults aged ≥55 years diagnosed with neovascular age-related macular degeneration (nAMD) in ≥1 eligible eye with a best-corrected visual acuity of 20/320 or better.
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