Smoking and tobacco use present significant public health challenges due to their association with high morbidity and mortality rates worldwide. Despite reductions in smoking rates in many developed countries, global tobacco consumption remains high, especially in developing regions. This review examines the chronic effects of smoking on the respiratory system, detailing the pathological changes in the lungs and the resultant respiratory illnesses such as chronic obstructive pulmonary disease and lung cancer. Additionally, the review explores the impact of smoking on other body systems, including cardiovascular, immune, gastrointestinal, nervous, and reproductive systems. The extensive health implications of smoking emphasize the need for comprehensive public health interventions to reduce tobacco use and mitigate its adverse effects on health.
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http://dx.doi.org/10.7759/cureus.66415 | DOI Listing |
Reprod Toxicol
January 2025
Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea; Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
This study aimed to establish the optimal cut-off values for urinary cotinine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)to determine smoking status in Korean women over 20 years of age and to assess the correlation of these biomarkers with reproductive health, particularly menopausal age, in postmenopausal women. Utilizing data from the 7th edition of the Korea National Health and Nutrition Examination Survey (2016- 2018), researchers included postmenopausal women aged 40-60 years who were within 5 years of menopause. Self-reported smoking status was aligned with biomarkers levels to calculate optimal cut-off values, classifying a total of 503 postmenopausal women into four groups: never smokers (cotinine <0.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Department of Engineering Management and Systems Engineering, George Washington University, Washington, DC, United States.
Background: Large language model (LLM) artificial intelligence chatbots using generative language can offer smoking cessation information and advice. However, little is known about the reliability of the information provided to users.
Objective: This study aims to examine whether 3 ChatGPT chatbots-the World Health Organization's Sarah, BeFreeGPT, and BasicGPT-provide reliable information on how to quit smoking.
PLoS One
January 2025
Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Introduction: A long-term engagement (LTE) intervention was embedded in a social marketing campaign aimed at motivating quit attempts among Canadian adult commercial tobacco users 35 to 64 years of age. The purpose of this study was to examine the effectiveness and appeal of LTE within a marketing campaign.
Methods: 3,199 Canadians who smoked cigarettes aged 35-64 recruited using Facebook and Instagram advertisements were randomized into Intervention and Control groups.
Biomarkers
January 2025
PMI R&D, Philip Morris Products S.A., Neuchâtel, Switzerland.
Background: Growing evidence indicates that noncombustible products could be a tobacco harm reduction tool for smokers who do not quit. The Tobacco Heating System (THS) emits substantially lower levels of harmful cigarette smoke constituents, and previous randomized clinical studies showed improved levels of biomarkers of potential harm (BoPH) linked to smoking-related disease.
Methods: In this cross-sectional study of healthy participants (n = 982) who (i) smoked cigarettes, (ii) had voluntarily switched from smoking to THS use, or (iii) formerly smoked, blood and urine samples were assayed for nine BoPH.
Addict Behav Rep
June 2025
Development Gateway: an IREX Venture, Washington, DC, United States.
Introduction: Tobacco use typically begins during adolescence. There is a lack of comprehensive evidence on the use of different tobacco products among adolescents in Africa.
Aims And Methods: We used the most recent Global Youth Tobacco Surveys from 53 African countries, covering 2003-2020, to estimate the overall and gender-specific prevalence of each type of tobacco product by country, Africa region, World Bank income group, and age group among adolescents aged 11-17 years.
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