AI Article Synopsis
- Accurate detection of organophosphate pesticides (OPs) is essential for food safety, and the study utilizes dendritic mesoporous silica spheres to enhance the fluorescent properties of gold nanoclusters (AuNCs).
- A new fluorescent method for detecting OPs was developed, based on the interaction of copper (Cu) and thiocholine, which affects fluorescence levels in the presence of OPs like paraoxon.
- The study offers a portable testing solution using a smartphone-compatible device, enabling on-site monitoring of paraoxon with an impressive limit of detection, emphasizing the potential for more efficient food analysis.
Article Abstract
Accurate detection of organophosphate pesticides (OPs) is paramount for ensuring food safety. Dendritic mesoporous silica sphere was employed to confine gold nanoclusters (AuNCs@dmSiO) to ameliorate fluorescent property of AuNCs. A AuNCs@dmSiO-based fluorescent method was developed for OPs sensing. Identification of Cu by AuNCs quenched AuNCs@dmSiO fluorescence. Interaction between Cu and generated thiocholine in catalysis of acetylcholinesterase (AChE) caused fluorescence enhancement. OPs, an inhibitor of AChE, suppressed thiocholine production to cause fluorescence quenching. Based on fluorescent variation, a fluorescent method was proposed for OPs by selecting paraoxon as a model within range of 0.05-25.0 ng/mL with a limit of detection (LOD) of 0.032 ng/mL. Besides, a portable test swab was prepared for on-site monitoring OP paraoxon with a smartphone-based 3D-printing portable device with a LOD of 0.65 ng/mL. This work is highlighted by the inspiration of designing highly fluorescent AuNCs, and the provision of a viable avenue for OPs-related food analysis.
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| http://dx.doi.org/10.1016/j.foodchem.2024.141120 | DOI Listing |
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