Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijrobp.2024.05.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Recent Advances in Strategies to Enhance Photodynamic and Photothermal Therapy Performance of Single-Component Organic Phototherapeutic Agents.
Adv Sci (Weinh)
January 2025
The Department of Medical Imaging, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Xingangzhong Road 466, Guangzhou, 518037, P. R. China.
Photodynamic therapy (PDT) and photothermal therapy (PTT) have emerged as promising treatment options, showcasing immense potential in addressing both oncologic and nononcologic diseases. Single-component organic phototherapeutic agents (SCOPAs) offer advantages compared to inorganic or multicomponent nanomedicine, including better biosafety, lower toxicity, simpler synthesis, and enhanced reproducibility. Nonetheless, how to further improve the therapeutic effectiveness of SCOPAs remains a challenging research area.
View Article and Find Full Text PDFAn optimized approach for container deployment driven by a two-stage load balancing mechanism.
PLoS One
January 2025
School of Humanities, Ningbo University of Finance and Economics, Ningbo, Zhejiang, China.
Lightweight container technology has emerged as a fundamental component of cloud-native computing, with the deployment of containers and the balancing of loads on virtual machines representing significant challenges. This paper presents an optimization strategy for container deployment that consists of two stages: coarse-grained and fine-grained load balancing. In the initial stage, a greedy algorithm is employed for coarse-grained deployment, facilitating the distribution of container services across virtual machines in a balanced manner based on resource requests.
View Article and Find Full Text PDFHow Does Diploic Space Thickness Change With Age?
J Craniofac Surg
January 2025
Division of Plastic and Reconstructive Surgery, The Warren Alpert Medical School of Brown University.
Background: Cranial defects from trauma, surgery, or congenital conditions require precise reconstruction to restore cranial vault integrity. Autogenous calvarial grafts are preferred for their histocompatibility and biomechanical properties, but their success depends on a well-developed diploic space. Although prior studies have described overall skull thickness development, less is known about how diploic thickness changes through adulthood.
View Article and Find Full Text PDFGenetic investigation of hydrogenases in suggests that redox balance via hydrogen cycling enables high ethanol yield.
Appl Environ Microbiol
January 2025
Centro de Engenharia Genética e Biologia Molecular (CBMEG), Universidade Estadual de Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Unlabelled: is an anaerobic and thermophilic bacterium that has been genetically engineered for ethanol production at very high yields. However, the underlying reactions responsible for electron flow, redox equilibrium, and how they relate to ethanol production in this microbe are not fully elucidated. Therefore, we performed a series of genetic manipulations to investigate the contribution of hydrogenase genes to high ethanol yield, generating evidence for the importance of hydrogen-reacting enzymes in ethanol production.
View Article and Find Full Text PDFOptimizing Exclusion Criteria for Clinical Trials of Persistent Lyme Disease Using Real-World Data.
Healthcare (Basel)
December 2024
Union Square Medical Associates, 595 Buckingham Way, Suite 350, San Francisco, CA 94132, USA.
Background/objectives: Although eligibility criteria for clinical trials significantly impact study outcomes, these criteria are often established without scientific justification, leading to delayed recruitment, small sample sizes, and limited study generalizability. Persistent Lyme disease (PLD) presents unique challenges due to symptom variability, inconsistent treatment responses, and the lack of reliable biomarkers, underscoring the need for scientifically justified eligibility criteria.
Objective: This study examines the effects of commonly used enrollment criteria on sample yield in PLD clinical trials using real-world data (RWD) from the MyLymeData patient registry.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!