Partial accelerated life tests (PALTs) are employed when the results of accelerated life testing cannot be extended to usage circumstances. This work discusses the challenge of different estimating strategies in constant PALT with complete data. The lifetime distribution of the test item is assumed to follow the power half-logistic distribution. Several classical and Bayesian estimation techniques are presented to estimate the distribution parameters and the acceleration factor of the power half-logistic distribution. These techniques include Anderson-Darling, maximum likelihood, Cramér von-Mises, ordinary least squares, weighted least squares, maximum product of spacing and Bayesian. Additionally, the Bayesian credible intervals and approximate confidence intervals are constructed. A simulation study is provided to compare the outcomes of various estimation methods that have been provided based on mean squared error, absolute average bias, length of intervals, and coverage probabilities. This study shows that the maximum product of spacing estimation is the most effective strategy among the options in most circumstances when adopting the minimum values for MSE and average bias. In the majority of situations, Bayesian method outperforms other methods when taking into account both MSE and average bias values. When comparing approximation confidence intervals to Bayesian credible intervals, the latter have a higher coverage probability and smaller average length. Two authentic data sets are examined for illustrative purposes. Examining the two real data sets shows that the value methods are workable and applicable to certain engineering-related problems.
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http://dx.doi.org/10.1038/s41598-024-71498-w | DOI Listing |
New Phytol
January 2025
Temasek Life Sciences Laboratory, 1 Research Link, National University of Singapore, Singapore, 117604, Singapore.
Mediator, a transcriptional coactivator, regulates plant growth and development by interacting with various transcriptional regulators. MEDIATOR15 (MED15) is a subunit in the Mediator complex potentially involved in developmental control. To uncover molecular functions of Arabidopsis MED15 in development, we searched for its interactors.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
January 2025
Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.
Background: Subjective wellbeing (SWB) is a crucial measure of life quality in older adults. Understanding its relationship with frailty may inform strategies to promote healthy aging.
Methods: We analyzed data for older adults aged ≥ 60 years old from Waves 3 and 4 of the China Health and Retirement Longitudinal Study.
J Transl Med
January 2025
Department of Hematology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, China.
Background: Targeting exportin1 (XPO1) with Selinexor (SEL) is a promising therapeutic strategy for patients with multiple myeloma (MM). However, intrinsic and acquired drug resistance constitute great challenges. SEL has been reported to promote the degradation of XPO1 protein in tumor cells.
View Article and Find Full Text PDFBMC Health Serv Res
January 2025
Balikesir Ataturk City Hospital, PM&R Clinic, Balikesir, Turkey.
Health service policies are evolving into qualified health care providing best possible outcomes as well as focused on patient satisfaction. Hence the qualification valued health care includes patient satisfaction measurements, it is suggested to get feedbacks during the assessment of outcomes from the patient's perspective. Aging of the world population accelerates demand on rehabilitation medicine which means recovering impairments so is directly related with quality of life.
View Article and Find Full Text PDFBMC Public Health
January 2025
School of Psychology, Northwest Normal University, Lanzhou, 730070, China.
Objective: The aging population represents a formidable global challenge, with China experiencing an accelerated demographic shift. While previous research has established a directional link between mental health literacy, social participation, and active aging, the moderating effect of socioeconomic status (SES) on these associations remains underexplored. This study sought to address this gap by employing moderated network analysis, in contrast to the total score approaches commonly used in prior literature.
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