AI Article Synopsis
- There is a growing need for approved vaccines against Yersinia pestis due to its persistent presence and risk of pandemics.
- Significant advancements have been made in vaccine development, but urgent collaboration in global funding and health systems is essential for quick clinical application.
- The focus is on preventing future outbreaks, especially those caused by antibiotic-resistant strains of the plague bacterium.
Article Abstract
There is a compelling demand for approved plague vaccines due to the endemicity of Yersinia pestis and its potential for pandemic spread. Whilst substantial progress has been made, we recommend that the global funding and health security systems should work urgently to translate some of the efficacious vaccines reviewed herein to expedite clinical development and to prevent future disastrous plague outbreaks, particularly caused by antimicrobial resistant Y. pestis strains.Content includes material subject to Crown Copyright © 2024.This is an open access article under the Open Government License ( http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/ ).
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379892 | PMC |
| http://dx.doi.org/10.1038/s41541-024-00958-1 | DOI Listing |
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