Atypical Presentation of Tenosynovial Giant Cell Tumor on the Hallucal Flexor Tendon Sheath: A Case Report.

J Am Podiatr Med Assoc

†Department of Pathology and Laboratory Medicine, Temple University School of Podiatric Medicine, Philadelphia, PA. Dr. Arriola is now with Department of Pathology, Cooper University Health Care, Camden, NJ, and Cooper Medical School of Rowan University, Camden, NJ.

Published: September 2024

AI Article Synopsis

  • - Tenosynovial giant cell tumor (TGCT) is a rare, usually benign neoplasm that can be aggressive, found mainly in joints and tendon sheaths, particularly in the fingers and less often in the feet.
  • - TGCT is classified into two subtypes: localized and diffuse, and its symptoms can mimic other conditions like lipomas or ganglion cysts, making diagnosis tricky.
  • - A case study on a 30-year-old woman presented with pain and a mass in her foot, which was diagnosed as TGCT after surgical excision and testing, highlighting the importance of advanced imaging and histology for accurate diagnosis and treatment.

Article Abstract

Tenosynovial giant cell tumor (TGCT) is a rare type of neoplasm that may be locally aggressive but is most often benign and can be divided into two subtypes: localized and diffuse. It tends to develop in the joints, bursae, and tendon sheaths primarily in the digits of the hand and less commonly in the forefoot. This soft-tissue mass has many possible differential diagnoses, including lipoma, ganglion cyst, plantar fibroma, and various sarcomas; surgical excision is usually indicated to reach a definitive diagnosis and rule out malignancy. We report a rare case of a 30-year-old woman with atypical plantar hallucal pain and a palpable mass on the plantar lateral aspect of the left hallux. Surgical excision and histopathologic evaluation confirmed a TGCT of the left hallucal flexor tendon sheath. Although it bears clinical resemblance to several other soft-tissue masses, TGCT has numerous pathognomonic features evident with advanced imaging and histologic analysis that help the physician obtain an accurate diagnosis and proceed with appropriate treatment.

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Source
http://dx.doi.org/10.7547/23-073DOI Listing

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