AI Article Synopsis
- Francisella tularensis endocarditis is a rare infection that's tough to diagnose, with only a handful of cases documented.* -
- The report discusses two new cases caused by the subsp. holarctica strain, highlighting their positive outcomes through antibiotic treatment and valve replacement surgery.* -
- Effective treatment typically involves ciprofloxacin and gentamicin, alongside surgical intervention when required, with suspicion of the infection guided by local epidemiology and patient exposure.*
Article Abstract
Francisella tularensis endocarditis is rare and difficult to diagnose, and only a few cases have been described. We report two new cases of endocarditis due to F. tularensis subsp. holarctica, with a favorable evolution after appropriate antibiotic therapy and valve replacement surgery, and review the 5 other cases reported in the literature. This rare infection may be suspected based on the local epidemiology and the patient's exposure factors. A regimen of ciprofloxacin and gentamicin, combined with surgical valve replacement if necessary, appears to be effective in treating F. tularensis endocarditis.
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| http://dx.doi.org/10.1007/s10096-024-04931-7 | DOI Listing |
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