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An Outbreak of Human Adenovirus Infection Among Children Post COVID-19 Pandemic in Southern China.
J Med Virol
December 2024
Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, People's Republic of China.
Human adenovirus (HAdV) is an important pathogen causing pediatric acute respiratory illness (ARI) before COVID-19 pandemic. Since January 2023, China has reported ARI outbreaks attributed to Mycoplasma pneumoniae and other respiratory viruses. In this study, a total of 276 737 pediatric patients with ARI were enrolled from January 2023 to April 2024.
View Article and Find Full Text PDFChinese advances in understanding and managing genitourinary tract infections caused by Mycoplasma genitalium, Mycoplasma hominis, and Ureaplasma urealyticum.
Arch Microbiol
November 2024
Institute of Pathogenic Biology, Basic Medical School, Hengyang Medical School, University of South China, Hengyang Central Hospital, Hengyang, 421001, China.
Mycoplasma genitalium, Ureaplasma urealyticum and Mycoplasma hominis are bacterial pathogens found in the genitourinary tract, implicated in a range of infections. In women, these infections including pelvic inflammatory disease, vaginitis, infertility, and cervical cancer, while in men, they can cause non-gonococcal urethritis, prostate cancer, among other conditions. These infections are a global health concern, with China identified as a country with a high prevalence.
View Article and Find Full Text PDFEvolution of the CRISPR-Cas9 defence system in following colonization of a novel bird host.
Microb Genom
November 2024
Univ. Bordeaux, INRAE, UMR BFP, F-33882, Villenave d'Ornon, France.
Article Synopsis
- CRISPR-Cas systems are bacterial defenses that help combat viruses and genetic elements, but little is known about their evolution in new environments.* -
- In a study of a poultry pathogen that shifted to a passerine host 30 years ago, researchers observed changes in CRISPR-Cas components, showing adaptations to new viral pressures.* -
- Over time, isolates exhibited a rise in non-functional CRISPR-Cas systems, coinciding with the passerine host's resistance evolution, indicating that this inactivation may have been crucial for bacterial adaptation and increased virulence.*
Epidemiological, clinical, and genotypic characteristics of pediatric infections: an 8-year survey in Suzhou, China in the pre- and post-COVID-19 eras.
Front Microbiol
October 2024
Department of Respiratory Medicine, Children's Hospital of Soochow University, Suzhou, China.
Article Synopsis
- This study explores the trends in respiratory infections among children in Suzhou, China, from 2016 to 2023, focusing on how these trends evolved through different pandemic phases.
- It analyzed data from over 113,000 patients and found that the positive detection rates of infections dropped during the pandemic but increased significantly afterward, particularly among children aged 6 and older.
- Genetic testing of pneumonia cases revealed high rates of macrolide resistance, with 97.3% of samples showing mutations, highlighting the need for informed clinical diagnosis and treatment strategies.
High Procalcitonin Does Not Always Indicate a Bacterial Infection.
Cureus
October 2024
Medicine, Doncaster Royal Infirmary, Doncaster, GBR.
Article Synopsis
- * The case involves a 77-year-old woman with a history of medullary thyroid cancer and other medical issues, who experienced recurrent aspiration pneumonia and severe dysphagia.
- * Despite her PCT levels remaining high (over 100 ng/L), her CRP and white blood cell counts were normal, leading doctors to speculate that her PCT elevation was likely due to her thyroid cancer metastases rather than an acute bacterial infection.*
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