The photochemical direct esterification of aldehydes with alcohols -generated acyl-bromides presented in this report is an attractive complementary addition to hitherto reported methods, as these are usually carried out in a two-step, one-pot procedure in order to avoid side reactions such as the oxidation of alcohols by halogen sources.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d4ob01237b | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Visible-Light-Induced Synthesis of Esters via a Self-Propagating Radical Reaction.
J Org Chem
January 2025
College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, People's Republic of China.
We herein disclose a visible-light-induced synthesis of aryl esters through the cross-dehydrogenative coupling of aldehydes with phenols using BrCCl, in which phenolate functions as both a substrate and a photosensitizer. This transition-metal- and photocatalyst-free visible-light-induced esterification is suitable for a wide range of substrates and gives moderate to excellent yields (up to 95%). Mechanistic studies provided evidence of a self-propagating radical reaction involving homolytic cleavage of the aldehydic C-H bond and the formation of acyl bromides.
View Article and Find Full Text PDFElectronic and geometric effects in an Au@NiO core-shell nanocatalyst on the oxidative esterification of aldehydes.
Nanoscale
January 2025
Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee 37235, USA.
Article Synopsis
- Strong metal-support interactions (SMSIs) are crucial for optimizing the stability, activity, and selectivity of catalysts in chemical reactions, especially in heterogeneous catalysis.
- The Au@NiO core-shell nanostructure stands out as an innovative SMSI system, helping to stabilize the gold nanoparticles while also allowing for tunable properties through its interaction with the nickel oxide shell.
- Research shows that the electronic interaction between Au and NiO enhances the catalytic activity for oxidizing intermediates in the esterification process, revealing lower activation energy and superior performance compared to individual Au and NiO surfaces.
Generation of a synthetic autochthonous microbiota responsible for the essential flavors and brewing properties of Daqu.
Food Res Int
December 2024
College of Bioengineering, Sichuan University of Science & Engineering, Yibin 644005, Sichuan, China.
Article Synopsis
- This study developed a cleaner version of medium-high-temperature Daqu (XQ) using specific microbial inoculations and compared its features with traditional Daqu (CQ).
- Results revealed that XQ exhibited superior liquefaction, saccharification, esterification activities, and moisture content compared to industry standards.
- Flavor analysis showed both Daqu types had similar profiles dominated by esters, alcohols, and acids, while microbial sequencing identified specific fungi and bacteria unique to each type, providing a foundation for creating safer fermented foods.
Flavor properties of post-heated fermented milk revealed by a comprehensive analysis based on volatile and non-volatile metabolites and sensory evaluation.
Curr Res Food Sci
October 2024
Department of Nutrition and Health, Key Laboratory of Functional Dairy, Co-constructed by Ministry of Education and Beijing Government, China Agricultural University, Beijing, 100190, China.
Existing research on the post-heating processing of fermented milk has primarily focused on single post-heating treatments and the texture, while research on how changes in metabolites during different post-heating treatments affect flavor and sensory properties is limited. This study investigates the changes in volatile metabolites in fermented milk treated at different post-heating temperatures to determine the characteristic aroma types and analyzes the changes in non-volatile metabolites associated with aroma-active compounds or their precursors to clarify the causes of the altered flavor and sensory properties. The results showed that in the 65 °C and 75 °C treatments, 63 volatile compounds were produced by Strecker degradation, lipid oxidation and esterification to produce ketones and aldehydes.
View Article and Find Full Text PDFMadecassic acid analogues with a five-membered A-ring and their cytotoxic activity.
Nat Prod Res
November 2024
Institute of Chemistry, Vietnam Academy of Science and Technology, Cau Giay, Hanoi, Viet Nam.
The structural modification of madecassic acid focused on the contraction of the six-membered A-ring to a five-membered ring, combined with the dehydration of 6-OH to form a new double bond and formation of the esterification or amidation at C-28. The synthesised structures were identified based on the analysis of their NMR and EIS-MS data. Eighteen new madecassic acid analogues were tested for their cytotoxicity against three cancer cell lines, including human mouth carcinoma (KB), human hepatocellular carcinoma (HepG2), and human lung carcinoma (A549) using the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!