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| http://dx.doi.org/10.47895/amp.v58i14.11353 | DOI Listing |
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Axillary lesion in a young adult ends up to a peculiar diagnosis: primitive neuro-ectodermal tumor (PNET) of ulnar nerve: a rare case report.
Ann Med Surg (Lond)
October 2024
Department of Pathology, Golsar Hospital, Rasht, Guilan, Iran.
Article Synopsis
- Primitive neuro-ectodermal tumor (PNET) is a rare and aggressive tumor mainly affecting children and young adults, with very few documented cases found in peripheral nerves.
- A 30-year-old male presented with symptoms leading to the discovery of a PNET in the axillary region, diagnosed through imaging and confirmed via histopathological analysis after surgical removal.
- Accurate diagnosis is essential, as treatment typically includes surgical resection combined with chemotherapy and radiotherapy, highlighting the need to consider PNET in differential diagnoses of masses in the axillary area.
Mechanical behaviour of granular materials undergoing grain dissolution.
Sci Rep
September 2024
Laboratory of Soil Mechanics, Swiss Federal Institute of Technology, Lausanne, Switzerland.
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- * A theoretical framework was introduced to understand the mechanical impacts of mineral dissolution, followed by oedometer tests on salt-sand mixtures at various stress states to analyze the effects.
- * The results indicated that particle dissolution impacts mechanical behavior based on salt content and stress state, and the study emphasizes the need to consider these effects in engineering, especially with ongoing climate changes.
Begin with the Ends in Mind.
Acta Med Philipp
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National Teacher Training Center for the Health Professions, University of the Philippines Manila.
Lasofoxifene as a potential treatment for aromatase inhibitor-resistant ER-positive breast cancer.
Breast Cancer Res
June 2024
The Ben May Department for Cancer Research, The University of Chicago, 929 East 57th Street GCIS W421C, Chicago, IL, 60637, USA.
Background: Breast cancers treated with aromatase inhibitors (AIs) can develop AI resistance, which is often driven by estrogen receptor-alpha (ERα/ESR1) activating mutations, as well as by ER-independent signaling pathways. The breast ER antagonist lasofoxifene, alone or combined with palbociclib, elicited antitumor activities in a xenograft model of ER + metastatic breast cancer (mBC) harboring ESR1 mutations. The current study investigated the activity of LAS in a letrozole-resistant breast tumor model that does not have ESR1 mutations.
View Article and Find Full Text PDFReducing Transmission of Airborne Respiratory Pathogens: A New Beginning as the COVID-19 Emergency Ends.
Environ Health Perspect
May 2024
Departments of Epidemiology and Environmental and Occupational Health, Colorado School of Public Health, Aurora, Colorado, USA.
Background: In response to the COVID-19 pandemic, new evidence-based strategies have emerged for reducing transmission of respiratory infections through management of indoor air.
Objectives: This paper reviews critical advances that could reduce the burden of disease from inhaled pathogens and describes challenges in their implementation.
Discussion: Proven strategies include assuring sufficient ventilation, air cleaning by filtration, and air disinfection by germicidal ultraviolet (UV) light.
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