Background: This study aimed to investigate the associations of time from waking to the first cigarette (TWFC) with all-cause mortality, cardiovascular disease (CVD) mortality and incident CVD among people smoking.
Methods: Data were from the UK Biobank, including 32 519 people smoking aged 40-70 years. TWFC was investigated using a touch-screen questionnaire. Outcomes included all-cause mortality and mortality from and incidence of CVD, ischemic heart disease (IHD) and stroke.
Results: Compared with participants reporting TWFC >120 min, those reporting TWFC between 61 and 120 min (HR, 1.30; 95% CI, 1.10-1.53), TWFC between 5 and 60 min (1.48, 1.30-1.70) and TWFC <5 min (1.65, 1.42-1.93) had a higher risk of all-cause mortality. Compared with participants reporting TWFC >120 min, those reporting TWFC between 5 and 60 min and TWFC <5 min had higher risks of CVD and IHD mortality and incident CVD and IHD, but those reporting TWFC between 61 and 120 min did not. The associations of TWFC with stroke mortality and incident stroke were not observed.
Conclusion: In this cohort study, a shorter TWFC was associated with higher risks of all-cause mortality, mortality from CVD and IHD, as well as incident CVD and IHD.
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http://dx.doi.org/10.1093/pubmed/fdae242 | DOI Listing |
J Therm Biol
December 2024
Laboratory of Sport, Expertise and Performance (EA 7370), French National Institute of Sport (INSEP), Paris, France. Electronic address:
Introduction: The relationship between blood distribution, body temperature, and sleep/wakefulness states is still unclear. The aim of the present study is to systematically review the potential beneficial effects of bedding strategies (e.g.
View Article and Find Full Text PDFWorld J Psychiatry
December 2024
Department of Anesthesia, People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Clinical Research Center for Anesthesia Management, Urumqi 830001, Xinjiang Uygur Autonomous Region, China.
Background: Owing to the particularities of their physical characteristics, older patients undergoing surgery under general anesthesia experience great surgical traumas. Thus, exploring more refined and individualized nursing approaches is an urgent need to mitigate the negative effects of surgery on such patients.
Aim: To analyze the influence of preoperative comprehensive education on anxiety, depression, pain, and sleep in older patients who underwent surgery under general anesthesia.
J Therm Biol
December 2024
Institute of Zoology, Slovak Academy of Sciences, Dúbravská cesta 9, 845 06 Bratislava, Slovakia. Electronic address:
Sleep is a fundamental physiological process conserved through evolution, from worms to humans. Understanding how temperature influences sleep is essential for comprehending the complexities of animal behavior, physiology, and their adaptations to thermal environments. This study explores the impact of temperature on sleep behavior and patterns in Drosophila melanogaster.
View Article and Find Full Text PDFSleep
December 2024
Department of Psychiatry and Psychotherapy, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
Study Objectives: Visual stimulation at 40 Hz is being tested as a non-invasive approach against dementias such as Alzheimer's disease. Applying it during sleep could increase convenience, duration, and efficacy of stimulation. Here, we tested the feasibility of 40 Hz visual stimulation during sleep in a proof-of-concept study.
View Article and Find Full Text PDFSleep Sci
December 2024
Departamento de Psicobiologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Melanin-concentrating hormone (MCH) and hypocretins (Hcrt) 1 and 2 are neuropeptides synthesized in the lateral hypothalamic area by neurons that are critical in the regulation of sleep and wakefulness. Their receptors are located in the same cerebral regions, including the frontal cortex and hippocampus. The present study aimed to assess whether 96 hours of paradoxical sleep deprivation alters the functioning of the MCH and hypocretin systems.
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