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A 33-year-old female presented with coryzal symptoms, facial swelling, severe haemorrhagic stomatitis, blistering oral mucositis, conjunctival injection and a sparse targetoid rash on the back and face, requiring admission to hospital. She had received the seasonal influenza vaccination 3 days prior to feeling unwell. Differential diagnosis included erythema multiforme major (EMM) secondary to the influenza vaccine or Mycoplasma pneumoniae-induced rash and mucositis (MIRM).
View Article and Find Full Text PDFStudy of the Correlation between the Extent and Clinical Severity, and the Histopathological Characteristics of Geographic Tongue.
Folia Morphol (Warsz)
November 2024
Postgraduate Program in Dentistry, Health Institute of Nova Friburgo, Fluminense Federal University, Nova Friburgo, Brazil.
Article Synopsis
- - The study investigates the relationship between the Geographic Tongue Area and Severity Index (GTASI) scores and the histopathological features of geographic tongue lesions, an oral condition with unclear causes.
- - Conducted with 40 participants, the results show that 60% had mild cases, with common histological traits observed, such as parakeratosis and basal layer hyperplasia, regardless of severity levels.
- - Findings indicate that while mild cases exhibit low inflammatory response, more severe cases show distinct histopathological features, suggesting a strong link between the clinical severity of geographic tongue and its histological characteristics.
Oral mucous membrane tarsal patch grafting: broadening indications and long-term outcomes.
Orbit
November 2024
Corneoplastic Unit, Queen Victoria Hospital NHS Foundation Trust, East Grinstead, UK.
Article Synopsis
- The study introduces a surgical technique called oral mucous membrane tarsal patch grafting (MMTPG) for treating tarsal surface abnormalities beyond the eyelid margin.
- It includes a retrospective analysis of 8 patients with various refractory tarsal conjunctival conditions, focusing on outcomes like corneal epitheliopathy, visual acuity, and patient symptoms.
- Results showed no recurrences of epithelial defects, improved visual acuity in five cases, and reduced medication needs, indicating MMTPG's effectiveness in difficult-to-treat conditions.
A Case Report on Acute Visual Loss With Ophthalmoplegia Following Spine Surgery.
Cureus
September 2024
Department of Ophthalmology, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Postoperative vision loss is an unusual but serious side effect that can occur after nonocular surgeries, particularly those involving the heart or spine. Various causes, including ischemic optic neuropathy, central retinal artery occlusion, central retinal vein occlusion, and ischemic orbital compartment syndrome, can cause this condition. Here, we present a case of a 28-year-old male patient who underwent spine surgery for cervicodorsal spine injury and experienced sudden, painless vision loss in his left eye following the surgery.
View Article and Find Full Text PDFCorrelation of Clinical Severity of Trachomatous Inflammation and Chlamydia trachomatis Bacterial Load.
Am J Trop Med Hyg
December 2024
Francis I. Proctor Foundation, University of California, San Francisco, California.
The purpose of this study was to investigate the correlation between bacterial load of Chlamydia trachomatis as measured from quantitative polymerase chain reaction (qPCR) and the relative clinical severity of trachomatous inflammation. Individuals with trachoma from rural communities in Ethiopia had photographs taken as well as swabs obtained of the upper tarsal conjunctivas. Conjunctival swabs were processed with PCR assay, which provided quantitative results of ocular chlamydial load.
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