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Association Between Urinary Rare Earth Element Levels and Metabolic Syndrome: A Cross-sectional Study in the Minority Population of Guangxi in China. | LitMetric

Association Between Urinary Rare Earth Element Levels and Metabolic Syndrome: A Cross-sectional Study in the Minority Population of Guangxi in China.

J Occup Environ Med

From the Department of Epidemiology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China (X.X., P.L., G.W., X.H., F.L., C.M., L.L., L.S., X.Z., X.Q.); Department of Maternal, Child and Adolescent Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China (S.L.); Department of Sanitary Chemistry, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China (D.H.); Guangxi Colleges and Universities Key Laboratory of Prevention and Control of Highly Prevalent Diseases, Guangxi Medical University, Nanning, Guangxi, China (X.L., S.L.); and School of Public Health, Guangxi Medical University, Nanning, Guangxi, China (X.L.).

Published: November 2024

AI Article Synopsis

  • - The study aimed to explore the link between rare earth elements (REEs) and metabolic syndrome (MetS) using data from a cohort in Guangxi, China.
  • - Results indicated that while REEs as a whole were not significantly linked to MetS, specific elements showed contrasting effects: La, Pr, and Nd were negatively associated with abdominal obesity, while Ce, Pr, Nd, and Dy were positively associated with hypertension.
  • - The research proposed a U-shaped relationship between combined REEs and MetS, suggesting potential protective effects against abdominal obesity but increased risks for high blood pressure.

Article Abstract

Objective: This study aimed to investigate the association between rare earth elements (REEs) and metabolic syndrome (MetS).

Methods: We used a cross-sectional design based on the baseline data of the Prospective Cohort Study of Chronic Diseases in Ethnic Minority Natural Population in Guangxi in China. Logistic regression and BKMR models were employed to evaluate the association between REEs and risk of MetS.

Results: Although REEs were not significantly associated with MetS, certain elements such as La, Pr, and Nd were negatively associated with abdominal obesity, whereas Ce, Pr, Nd, and Dy were positively associated with hypertension. BKMR models suggested a U-shaped relationship between mixed REEs and MetS, with varying effects on abdominal obesity and high blood pressure.

Conclusions: This study suggests that exposure to REEs may be associated with a reduced risk of abdominal obesity and an increased risk of high blood pressure.

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Source
http://dx.doi.org/10.1097/JOM.0000000000003217DOI Listing

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