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http://dx.doi.org/10.1016/j.jham.2024.100070 | DOI Listing |
Microsc Microanal
January 2025
Fritz-Haber-Institut der Max-Planck-Gesellschaft, Berlin 14195, Germany.
In catalysis research, the amount of microscopy data acquired when imaging dynamic processes is often too much for nonautomated quantitative analysis. Developing machine learned segmentation models is challenged by the requirement of high-quality annotated training data. We thus substitute expert-annotated data with a physics-based sequential synthetic data model.
View Article and Find Full Text PDFCurr Biol
January 2025
Department of Biology, Rosenstiel Basic Medical Science Research Center, Brandeis University, 415 South Street, Waltham, MA 02454, USA. Electronic address:
In vivo functions of the septin and actin cytoskeletons are closely intertwined, yet the mechanisms underlying septin-actin crosstalk have remained poorly understood. Here, we show that the yeast-bud-neck-associated Fes/CIP4 homology Bar-amphiphysin-Rvs (F-BAR) protein suppressor of yeast profilin 1 (Syp1)/FCHo uses its intrinsically disordered region (IDR) to directly bind and bundle filamentous actin (F-actin) and to physically link septins and F-actin. Interestingly, the only other F-BAR protein found at the neck during bud development, Hof1, has related activities and also potently inhibits the bud-neck-associated formin Bnr1.
View Article and Find Full Text PDFis a species closely linked to human health. This study investigated the acaricidal efficacy of methanol extracts from 18 traditional Chinese medicinal plants against . The extract from DC.
View Article and Find Full Text PDFAnal Chim Acta
January 2025
Department of Chemistry, National Chung Hsing University, Taichung City, 402202, Taiwan, ROC. Electronic address:
Background: To integrate valves, manifolds, and solid-phase extraction (SPE) columns into a compact device is technically difficult. Four-dimensional printing (4DP) technologies, employing stimuli-responsive materials in three-dimensional printing (3DP), are revolutionizing the fabrication, functionality, and applicability of stimuli-responsive analytical devices that can show time-dependent shape programming to enable more complex geometric designs and functions. However, 4D-printed stimuli-responsive actuators and valves utilized to control flowing streams in SPE applications remain rare.
View Article and Find Full Text PDFExp Ther Med
February 2025
Department of Infectious Diseases, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361000, P.R. China.
Sepsis, a condition characterized by a dysregulated host response to infection, can progress to septic shock and lead to various complications. The present study aimed to identify risk factors for the early clinical identification of sepsis patients at heightened risk of complications. In the present study, a total of 383 hospitalized patients with sepsis and positive blood cultures were enrolled.
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