Objectives: This study attempted to develop 2 biodegradable periodontal chips containing (miswak) or benzyl isothiocyanate (BITC) extracts and evaluate their clinical effectiveness in managing periodontitis.
Methods: This clinical trial was conducted at the Faculty of Dentistry, Universiti Teknologi MARA Shah Alam, Selangor, Malaysia, from September 2010 to April 2012. Periodontal chips were formulated using , benzyl isothiocyanate (BITC) and chitosan extracts. All patients were treated with full mouth scaling and root planing at baseline. Thereafter, the periodontal pockets (≥5 mm in length) were divided into 4 groups: the control group; group 2 (plain chitosan chip); group 3 ( extract); and group 4 (BITC extract). Plaque index (PI), bleeding on probing (BOP), periodontal probing pocket depth and clinical attachment levels were recorded at days 0 and 60 only.
Results: A total of 12 patients participated in this study. Overall, 240 periodontal pockets were evaluated. The study revealed significant improvements in PI, BOP and reduction in periodontal pocket depth in all 4 groups ( <0.05). The improvement in clinical attachment level was significantly higher ( <0.001) among the group that received chips compared to the control and other chip-treated groups.
Conclusion: Periodontal chips containing can be used as adjuncts to treat patients with periodontitis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11370949 | PMC |
| http://dx.doi.org/10.18295/squmj.6.2024.030 | DOI Listing |
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