Background: Lung ultrasound (LUS) is an evolving point-of-care tool in the neonatal intensive care unit. LUS score has been evaluated in adults as well as in neonates to characterize and diagnose various respiratory conditions. Recently, the LUS score has been evaluated for predicting clinical respiratory outcomes in neonates.
Objective: To assess the association between LUS score and various modes of respiratory support and clinical outcomes among neonates presenting with respiratory distress.
Methods: In this prospective, cross-sectional, observational study done in a tertiary care neonatal unit, the LUS score was calculated within three hours of receiving respiratory support. Subsequently, the LUS score was assigned with each escalation and de-escalation of respiratory support. Maximum LUS scores for each clinical outcome were also recorded. Inter-rater agreement was determined with the intraclass correlation coefficient.
Result: A total of 162 LUS scans were performed in 65 babies with a mean gestation of 32.4 ± 3.7 weeks and median (IQR) birth weight of 1480 (1130-2000) grams. The LUS scores (median (IQR)) of babies on continuous positive airway pressure (CPAP), noninvasive positive pressure ventilation (NIPPV), and mechanical ventilation (MV) were 4 (3-6.5), 9 (8-11), and 12 (11-13.5), respectively (p-value < 0.001). The difference in maximum median LUS scores between different clinical outcomes was statistically significant, with a p-value < 0.001. LUS score had an excellent inter-rater agreement (intraclass correlation coefficient = 0.998; p-value < 0.001).
Conclusion: There is an association between LUS score and different modes of respiratory support with scores increasing as the level of support increased. LUS score was also found to be related with clinical outcomes like death, extubation failure, and recovery, which could help in predicting the prognosis.
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http://dx.doi.org/10.7759/cureus.66199 | DOI Listing |
Diagnostics (Basel)
December 2024
Pediatric Clinic, Parma University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Neonatal respiratory distress syndrome (RDS) is a common and potentially life-threatening condition in preterm infants, primarily due to surfactant deficiency. Early and accurate diagnosis is critical to guide timely interventions such as surfactant administration and respiratory support. Traditionally, chest X-rays have been used for diagnosis, but lung ultrasound (LUS) has gained prominence due to its non-invasive, radiation-free, and bedside applicability.
View Article and Find Full Text PDFJ Clin Anesth
December 2024
Department of Anesthesiology, Second Affiliated Hospital of Harbin Medical University, China; The Key Laboratory of Anesthesiology and Intensive Care Research of Heilongjiang Province, China. Electronic address:
Study Objective: To determine whether individualized fraction of inspired oxygen (iFiO) improves pulmonary atelectasis after elective laparoscopic colorectal surgery relative to 60 % FiO.
Design: This was a single-center, prospective, randomized study.
Setting: This study was conducted in a single tertiary care hospital in China.
Ann Ital Chir
December 2024
Department of Anesthesiology, Institute of Anesthesia, Emergency and Critical Care, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, 225002 Yangzhou, Jiangsu, China.
Aim: Intraoperative lung-protective ventilation strategies (LPVS) have been shown to improve lung oxygenation and prevent postoperative pulmonary problems in surgical patients. However, the application of positive end-expiratory pressure (PEEP)-based LPVS in emergency traumatic brain injury (TBI) has not been thoroughly explored. The purpose of this study is to evaluate the effects of drive pressure-guided individualized PEEP on perioperative pulmonary oxygenation, postoperative pulmonary complications, and recovery from neurological injury in patients with TBI.
View Article and Find Full Text PDFCurr Med Imaging
December 2024
Department of Ultrasound, The Affiliated Hospital, Southwest Medical University, 319 Zhongshan Road, LuZhou 646000, Sichuan, P.R. China.
Severe pneumonia (SP) is a common cause of septic shock and Acute Respiratory Distress Syndrome (ARDS), leading to multiorgan dysfunction syndrome. Patients with SP often require respiratory support, and SP is associated with high mortality and is a significant economic burden for hospitalized patients. Therefore, early identification and real-time monitoring of the severity of SP are crucial for improving outcomes.
View Article and Find Full Text PDFPeerJ
December 2024
Department of Intensive Care Unit, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.
Background: Pre-operative pulmonary function testing (PFT) plays a key role in predicting postoperative complications or functional impairment. However, PFT requires the subject and examiner to cooperate and the results are influenced by both technical and personal factors. In contrast, the use of ultrasound (US) for structural and functional assessments of the lungs and diaphragm is on the rise, as it requires minimal patient cooperation.
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