AI Article Synopsis
- Alveolar bone loss often occurs after tooth extraction, and this study evaluated the effectiveness of two biomaterials (HA/β-TCP and PLGA) in reducing this loss.
- The research involved 24 extraction sites from impacted mandibular third molars, with each biomaterial placed in different sockets to measure their resorption rates over a year.
- Results showed that while both materials helped with bone preservation, HA/β-TCP led to slightly more resorption than PLGA, suggesting that PLGA may be a better option for maintaining alveolar bone height post-extraction.
Article Abstract
Background: Alveolar Bone loss occurs frequently during the first six months after tooth extraction. Various studies have proposed different methods to reduce as much as possible the atrophy of the alveolar ridge after tooth extraction. Filling the socket with biomaterials after extraction can reduce the resorption of the alveolar ridge. We compared the height of the alveolar process at the mesial and distal aspects of the extraction site and the resorption rate was calculated after the application of HA/β-TCP or synthetic co-polymer polyglycolic - polylactic acid PLGA mixed with blood to prevent socket resorption immediately and after tooth extraction.
Methods: The study was conducted on 24 extraction sockets of impacted mandibular third molars bilaterally, vertically, and completely covered, with a thin bony layer. HA/β-TCP was inserted into 12 of the dental sockets immediately after extraction, and the synthetic polymer PLGA was inserted into 12 of the dental sockets. All sockets were covered completely with a full-thickness envelope flap. Follow-up was performed for one year after extraction, using radiographs and stents for the vertical alveolar ridge measurements.
Results: The mean resorption rate in the HA/β-TCP and PLGA groups was ± 1.23 mm and ± 0.1 mm, respectively. A minimal alveolar bone height reduction of HA/β-TCP was observed after 9 months, the reduction showed a slight decrease to 0.93 mm, while this rate was 0.04 mm after 9 months in the PLGA group. Moreover, the bone height was maintained after three months, indicating a good HA/β-TCP graft performance in preserving alveolar bone (1.04 mm) while this rate was (0.04 mm) for PLGA.
Conclusion: The PLGA graft demonstrated adequate safety and efficacy in dental socket preservation following tooth extraction. However, HA/β-TCP causes greater resorption at augmented sites than PLGA, which clinicians should consider during treatment planning.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11375842 | PMC |
| http://dx.doi.org/10.1186/s12903-024-04803-8 | DOI Listing |
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