AI Article Synopsis
- Cancer is the second leading cause of death globally and has become a growing issue in Kazakhstan, particularly in Almaty, where common cancers include lung and prostate cancers in men and breast and cervical cancers in women.
- From 2017 to 2021, the study found that these cancers contributed to a total disability-adjusted life years (DALYs) burden of 25,016.60 in 2021, with the majority of this burden coming from mortality rather than disability, notably showing higher rates of non-fatal outcomes in women.
- While the overall cancer burden is rising, some specific cancers are declining, indicating that cancer control strategies are effective, highlighting the importance of ongoing prevention and awareness efforts, including HPV vaccination and cancer screenings.
Article Abstract
Globally, cancer is the second leading cause of death, with a growing burden also observed in Kazakhstan. This study evaluates the burden of common cancers in Almaty, Kazakhstan's major city, from 2017 to 2021, utilizing data from the Information System of the Ministry of Health. In Kazakhstan, most common cancers among men include lung, stomach, and prostate cancer, while breast, cervical, and colorectal cancers are predominant among women. Employing measures like disability-adjusted life years (DALYs), we found that selected cancer types accounted for a total DALY burden of 25,016.60 in 2021, with mortality contributing more than disability (95.2% vs. 4.7%) with the ratio of non-fatal to fatal outcomes being 1.4 times higher in women than in men. The share of non-fatal burden (YLD) proportion within DALYs increased for almost all selected cancer types, except stomach and cervical cancer over the observed period in Almaty. Despite the overall increase in cancer burden observed during the time period, a downward trend in specific cancers suggests the efficacy of implemented cancer control strategies. Comparison with global trends highlights the significance of targeted interventions. This analysis underscores the need for continuous comprehensive cancer control strategies in Almaty and Kazakhstan, including vaccination against human papillomavirus, stomach cancer screening programs, and increased cancer awareness initiatives.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11375099 | PMC |
| http://dx.doi.org/10.1038/s41598-024-71449-5 | DOI Listing |
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