AI Article Synopsis

  • A 75-year-old Japanese man experienced severe left-sided chest pain for four months, leading to the discovery of angiosarcoma after imaging and histopathological examination revealed the cancer's presence linked to his chronic tuberculosis.
  • Despite initial treatment with paclitaxel chemotherapy, it was ineffective after three months, underscoring the importance of monitoring patients with chronic pyothorax for potential malignant developments.

Article Abstract

Angiosarcoma is a rare malignancy that can arise from chronic pyothorax. We herein report a 75-year-old Japanese man with a history of tuberculosis who presented with left-sided chest pain that had persisted for 4 months. Chest computed tomography revealed an encapsulated left-sided pleural effusion with chest wall invasion, and histopathology confirmed angiosarcoma arising from a chronic tuberculous pyothorax. Chemotherapy with paclitaxel (80 mg/m weekly) was ineffective and was discontinued after 3 months. Our findings emphasize that physicians should inform patients with chronic tuberculous pyothorax about malignant complications for which chest pain is the initial symptom, in addition to highlighting the need for careful follow-up.

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Source
http://dx.doi.org/10.2169/internalmedicine.4088-24DOI Listing

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