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| http://dx.doi.org/10.1055/a-2388-7169 | DOI Listing |
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The Impact of subsp. on Intestinal Microbial Community Composition and Diversity in Small-Tail Han Sheep.
Pathogens
December 2024
College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010010, China.
Paratuberculosis (PTB), primarily caused by subsp. (MAP), is a chronic infection that affects ruminants and is difficult to prevent, diagnose, and treat. Investigating how MAP infections affect the gut microbiota in sheep can aid in the prevention and treatment of ovine PTB.
View Article and Find Full Text PDFGreen Radish Polysaccharides Ameliorate Hyperlipidemia in High-Fat-Diet-Induced Mice via Short-Chain Fatty Acids Production and Gut Microbiota Regulation.
Foods
December 2024
Department of Food Science and Engineering, College of Food Science and Engineering, Bohai University, Jinzhou 121013, China.
The objective of this study was to examine the hypolipidemic effect and potential mechanism of action of green radish polysaccharide (GRP) in hyperlipidemic mice. We found that in mice fed a high-fat diet, supplementing with GRP reduced body weight and liver index, significantly improved serum lipid levels and markers of liver damage, and mitigated oxidative stress and inflammation. Mechanistically, in these hyperlipidemic mice, the size of fat cells was reduced by GRP, and the abnormal accumulation of lipid droplets was reduced.
View Article and Find Full Text PDFDiagnostic value of SAT-TB in stool and urine samples for intestinal and urinary tuberculosis.
Diagn Microbiol Infect Dis
December 2024
State Key Laboratory of Respiratory Disease, Guangzhou Key Laboratory of Tuberculosis Research, Department of Tuberculosis, Guangzhou Chest Hospital, Institute of Tuberculosis, Guangzhou Medical University, Guangdong 510095, PR China. Electronic address:
Background: The simultaneous amplification/testing for tuberculosis (SAT-TB) targets specific 16s rRNA for detecting Mycobacterium tuberculosis in real-time.
Objective: To evaluate SAT-TB's performance in detecting intestinal and urinary TB using stool and urine samples.
Methods: Stool (94) and urine samples (69) (From 2021 to 2022), were collected from pulmonary combined with suspected intestinal or urinary tuberculosis.
A comprehensive review of paratuberculosis in animals and its implications for public health.
Open Vet J
November 2024
Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Paratuberculosis is an infectious disease caused by subspecies (MAP). Typically, ruminant animals including cattle, buffalo, goats, and sheep are infected with MAP. Animals get infected with MAP in a number of ways, such as by eating or drinking contaminated food or water, or by nursing from an infected mother who may have contaminated teats or directly shed the organism in milk or colostrum.
View Article and Find Full Text PDFRemote disruption of intestinal homeostasis by Mycobacterium abscessus is detrimental to Drosophila survival.
Sci Rep
December 2024
Université Paris-Saclay, UVSQ, LGBC, 78000, Versailles, France.
Mycobacterium abscessus (Mabs), an intracellular and opportunistic pathogen, is considered the most pathogenic fast-growing mycobacterium, and causes severe pulmonary infections in patients with cystic fibrosis. While bacterial factors contributing to its pathogenicity are well studied, the host factors and responses that worsen Mabs infection are not fully understood. Here, we report that Mabs systemic infection alters Drosophila melanogaster intestinal homeostasis.
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