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An Acellular Platform to Drive Urinary Bladder Tissue Regeneration.
Adv Ther (Weinh)
January 2025
Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Division of Pediatric Urology, Department of Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA; Center for Regenerative Nanomedicine, Northwestern University, Chicago, IL 60611, USA; Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.
Impaired bladder compliance secondary to congenital or acquired bladder dysfunction can lead to irreversible kidney damage. This is managed with surgical augmentation utilizing intestinal tissue, which can cause stone formation, infections, and malignant transformation. Co-seeded bone marrow mesenchymal stem cell (MSC)/CD34+ hematopoietic stem cell (HSPC) scaffolds (PRS) have been successful in regenerating bladder tissue.
View Article and Find Full Text PDFAutologous Micro-Fat Transplantation for Facial Sunken Treatment: Single-Center Experience.
J Craniofac Surg
November 2024
Department of Plastic & Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Background: Facial sunken deformities, congenital or acquired, are common in clinical practice for the reduction of soft or hard tissues. In clinical practice, filler injection and tissue transplantation are often used to improve facial contour. Among these, autologous fat grafting for treating facial contour defects is most common in clinical practice.
View Article and Find Full Text PDFPrecision Medicine in Congenital Heart Disease, Rheumatic Heart Disease, and Kawasaki Disease of Children: An Overview of Literature.
Cardiol Rev
May 2024
Department of Pediatrics, University of Nebraska Medical Center, Omaha, NE.
Congenital heart disease and common acquired heart diseases like Kawasaki disease and rheumatic heart disease are prevalent cardiovascular conditions in children worldwide. Despite the availability of treatment options, they continue to be significant contributors to morbidity and mortality. Advancements in early diagnosis, improvements in treatment approaches, and overcoming resistance to available treatments are crucial to reduce morbidity.
View Article and Find Full Text PDFDaily executive functioning in adults with pediatric hemispherectomy.
Epilepsy Res
January 2025
Fuller Graduate School of Psychology, Travis Research Institute, Pasadena, CA 91101, United States; International Research Consortium for the Corpus Callosum and Cerebral Connectivity (IRC5), Pasadena, CA 91106, United States; California Institute of Technology, Division of Humanities and Social Sciences, Pasadena, CA 91125, United States. Electronic address:
Background And Aims: For young children with intractable epilepsy caused by congenital abnormalities or acquired cortical lesions, pediatric hemispherectomy surgery (pHS) may offer the only path to seizure remediation. Although some sensory and motor outcomes of pHS are highly predictable, the long-term cognitive and functional sequelae of pHS are far more variable. With the aim of identifying potential post-pHS intervention targets, the current study examined daily executive functioning and self-awareness in adults with pHS and broadly intact cognitive outcomes (indicated by average or above performance on intelligence tests).
View Article and Find Full Text PDFOral Blue Nevus of the Lingual Gingiva: A Case Report.
Cureus
January 2025
College of Dentistry, King Saud University, Riyadh, SAU.
Oral melanocytic nevi (OMN) are rare benign tumors originating from melanocytes with an unclear pathogenesis. The current theory suggests that OMN originate from dormant dendritic melanocytes that become enclosed in the dermis during the embryonic migration of melanoblasts - the precursors of melanocytes - from the neural crest to the epidermis. OMN can be congenital or acquired, with acquired nevi being more common.
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