Lung involvement in children with congenital cytomegalovirus infection has been scarcely described. We describe three new cases of persistent pulmonary hypertension in children with congenital cytomegalovirus and review the other seven cases reported in the literature since 1988. All children had a symptomatic infection, including severe central nervous system or visceral findings. Morbidity and mortality were high. Persistent pulmonary hypertension may be a rare complication in severely symptomatic congenital cytomegalovirus infants. It is important to screen for congenital cytomegalovirus in cases of idiopathic refractory persistent pulmonary hypertension. Intensive treatment should be undertaken to treat this potentially rare lung involvement in combination with antiviral treatment.
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http://dx.doi.org/10.1111/cga.12580 | DOI Listing |
Infect Drug Resist
December 2024
Beijing Institute of Tropical Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
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View Article and Find Full Text PDFImmun Ageing
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ICMR-National Institute of Translational Virology and AIDS Research (formerly ICMR-National AIDS Research Institute), 73, G block, MIDC, Bhosari, Pune, 411026, India.
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View Article and Find Full Text PDFMod Rheumatol Case Rep
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Department of Rheumatology and Clinical Immunology, Wakayama Medical University, Wakayama, Japan.
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View Article and Find Full Text PDFJ Med Virol
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King Fahad Military Medical Complex, Ministry of Defense Health Services, Dhahran, Saudi Arabia.
The high prevalence of cytomegalovirus (CMV) after kidney transplantation, along with its significant morbidity, mortality, and financial burden, makes it a serious infectious complication. This retrospective observational study aimed to determine the incidence of CMV infection and recurrence in renal transplant recipients during the era of immunosuppression (IS), and to identify modifiable predictors of CMV infection. A total of 233 patients were screened for CMV disease incidence and predictors and were prospectively followed.
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