AI Article Synopsis

  • Achalasia is a rare condition where the lower esophageal sphincter doesn't relax properly, leading to difficulty swallowing, and the main treatment options are Laparoscopic Heller Myotomy (LHM) and Peroral Endoscopic Myotomy (POEM).
  • Recent studies indicate that both LHM and POEM show similar long-term success rates after 5 years, but patients who undergo POEM are more likely to experience gastroesophageal reflux disease (GERD) than those who have LHM.
  • The choice of treatment can depend on the type of achalasia, and while some evidence suggests POEM might be better for type III patients, more research is needed for long-term results and to tailor treatments to individual patient

Article Abstract

Achalasia is a rare esophageal motility disorder characterized by nonrelaxation of the lower esophageal sphincter. Laparoscopic Heller myotomy (LHM) is the gold standard treatment for achalasia. Peroral endoscopic myotomy (POEM), a less invasive treatment, is performed extensively, and the selection of the intervention method remains debatable to date. In addition to the availability of extensive studies on short-term outcomes, recent studies on the long-term outcomes of LHM and POEM have shown similar clinical success after 5 y of follow-up. However, gastroesophageal reflux disease (GERD) was more common in patients who had undergone POEM than in those who had undergone LHM. Moreover, existing studies have compared treatment outcomes in various disease states. Some studies have suggested that POEM is superior to LHM for patients with type III achalasia because POEM allows for a longer myotomy. Research on treatment for sigmoid types is currently in progress. However, the long-term results comparing LHD and POEM are insufficient, and the best treatment remains controversial. Further research is needed, and treatment options should be discussed with patients and tailored to their individual needs and pathologies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11368501PMC
http://dx.doi.org/10.1002/ags3.12807DOI Listing

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