Emamectin Benzoate, a potent pesticide extensively used in agriculture, has raised concerns due to its potential for severe poisoning. While its safety in mammals is attributed to limited blood-brain barrier penetration and reduced affinity for specific channels, Emamectin Benzoate Poisoning can unexpectedly manifest with severe symptoms. Predominantly resulting from intentional ingestion, clinical presentations involve central nervous system depression, respiratory distress, gastrointestinal symptoms, and sore throat. Formulation solvents enhance toxicity, leading to corrosive injuries and metabolic imbalances. Skin contact induces irritation. Diagnosis relies on clinical evaluation, lacking specific laboratory data. Treatment lacks a designated antidote; hence, decontamination and cautious symptomatic management play pivotal roles. Severe cases require vigilant monitoring, with intensive care unit admission calling for altered consciousness and respiratory distress.
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http://dx.doi.org/10.6705/j.jacme.202409_14(3).0001 | DOI Listing |
Molecules
December 2024
Key Laboratory of Biopesticide and Chemical Biology, Ministry of Education, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Emamectin benzoate (EB) is a highly effective broad-spectrum insecticide and acaricide. However, because EB is easily degraded, the conventional formulations of EB are often overapplied. In this study, polylactic acid (PLA)-based microspheres were prepared using the modified solvent evaporation method for the controlled release of EB.
View Article and Find Full Text PDFJ Hazard Mater
December 2024
Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment, Nanjing 210042, China. Electronic address:
Emamectin benzoate (EMB) is a widely used insecticide that can accumulate in aquatic environments under specific conditions of high application intensity or improper management, posing potential risks to aquatic organisms and human health. This study aimed to evaluate the reproductive toxicity of long-term EMB exposure in zebrafish (Danio rerio) and neurodevelopmental toxicity in their offspring. Zebrafish embryos were exposed to various concentrations of EMB (0, 0.
View Article and Find Full Text PDFFront Neurol
December 2024
Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China.
Background: Emamectin·chlorfenapyr is a compound comprising chlorfenapyr and emamectin benzoate that is widely used in agriculture. Chlorfenapyr toxicity has been verified in animals; however, its true mechanism and progression in humans remain to be elucidated. Cases of emamectin·chlorfenapyr poisoning are seldom.
View Article and Find Full Text PDFBMC Genomics
December 2024
Institute of Aquaculture, University of Stirling, Stirling, Scotland, UK.
Background: The salmon louse (Lepeophtheirus salmonis) is a parasite of wild and farmed salmonid fish, causing huge economic damage to the commercial farming of Atlantic salmon (Salmo salar) in the northern hemisphere. The avermectin emamectin benzoate (EMB) is widely used for salmon delousing. While resistance to EMB is widespread in Atlantic populations of L.
View Article and Find Full Text PDFPest Manag Sci
December 2024
College of Plant Protection, Nanjing Agricultural University, State and Local Joint Engineering Research Centre of Green Pesticide Invention and Application, Nanjing, China.
Background: The rice stem borer, Chilo suppressalis Walker (Lepidoptera: Crambidae), is a damaging pest of rice worldwide. Following the evolution of C. suppressalis resistance to diamide and abamectin insecticides, emamectin benzoate (EB) became a key insecticide for the control of this species in China.
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