Fatty liver disease - non alcoholic to metabolic - A transition of concepts!!

J Family Med Prim Care

Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research (Deemed to be University), Wardha, Maharashtra, India.

Published: August 2024

AI Article Synopsis

  • Metabolic dysfunction associated fatty liver disease (MAFLD) is a new concept defined by experts, highlighting the importance of factors like diabetes, obesity, and metabolic dysregulation alongside the absence of alcohol intake for diagnosis.
  • A consensus on MAFLD criteria aims to enhance clinical protocols, improving diagnosis, treatment, and research in liver diseases globally.
  • Early recognition of MAFLD is crucial as it significantly increases the risk of serious health issues, making it essential in family medicine and primary care.

Article Abstract

Metabolic dysfunction associated fatty liver disease (MAFLD) was a concept suggested lately. Initially, the only criterion for the diagnosis of MAFLD was the absence of alcohol intake. With rising prevalence and studies assessing this condition, certain "positive criteria" were put forth. Experts from 22 countries proposed a simple yet comprehensive definition for the condition independent of other liver diseases. The presence of hepatic steatosis in addition to diabetes mellitus type 2, metabolic dysregulation, and obesity is generally observed. Criteria to define MAFLD-associated cirrhosis were also proposed. Reaching an agreement on MAFLD criteria will help define a protocol (for example: for International classification of Diseases (ICD) - coding), which will improve clinical care and advance the clinical and scientific field of liver research. As it is a condition that increases the risk of diabetes mellitus, chronic kidney disease (CKD), cirrhosis, hepatocellular carcinoma, and cardiac disorders it is important to recognize it at an early stage which makes it essential part of family medicine and primary care.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11368329PMC
http://dx.doi.org/10.4103/jfmpc.jfmpc_1863_21DOI Listing

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