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miR-145b/AP2B1 Axis Contributes to Noise-induced Sensorineural Hearing Loss In a Male Mouse Model.
Cell Biochem Biophys
January 2025
Department of Otolaryngology, Head and Neck Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China.
Sensorineural hearing loss (SNHL) is an increasingly prevalent sensory disorder, but the underlying mechanisms remain poorly understood. Adaptor related protein complex 2 subunit beta 1 (AP2B1) has been indicated to be detectable in mature cochleae. Nonetheless, it is unclear whether AP2B1 is implicated in the progression of SNHL.
View Article and Find Full Text PDFCan switching stimulus polarity identify Meniere's disease? A preliminary investigation on ABR.
Acta Otolaryngol
January 2025
School of Audiology and Speech Language Pathology, Bharati Vidyapeeth (Deemed to be University), Pune, India.
Background: Meniere's disease (MD) affects 0.2% to 0.5% of the global population, with regional variations.
View Article and Find Full Text PDFMetabolome modification and underlying biomarker of noise-induced hearing loss Guinea pig cochlear fluid.
Acta Otolaryngol
January 2025
Department of Otolaryngology Head and Neck Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing, China.
Background: Noise-induced hearing loss (NIHL) is a kind of acquired sensorineural hearing loss and has shown an increasing incidence in recent years. Hence, elucidating the exact pathophysiological mechanisms and proposing effective treatment and prevention methods become the top priority. Though a great number of researches have been carried out on NIHL, few of them were focused on metabolites.
View Article and Find Full Text PDFEffect of hearing experience on preschool-aged children's eye gaze to a talker during spoken language processing.
Atten Percept Psychophys
January 2025
School of Allied Health and Communicative Disorders, Northern Illinois University, DeKalb, IL, USA.
Speechreading-gathering speech information from talkers' faces-supports speech perception when speech acoustics are degraded. Benefitting from speechreading, however, requires listeners to visually fixate talkers during face-to-face interactions. The purpose of this study is to test the hypothesis that preschool-aged children allocate their eye gaze to a talker when speech acoustics are degraded.
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