A novel selenium dioxide promoted selenylation/cyclization of leucosceptrane sesterterpenoids was reported. Two types of leucosceptrane derivatives with different valence states of selenium atoms (Se and Se) were obtained. The mechanisms of these two processes were proposed, and the selenium-containing derivates may serve as intermediates of Riley oxidation that could be trapped with appropriate substrates. Immunosuppressive activity screening revealed that 10 and 11 had obvious inhibitory effects on IFN-γ production, with IC values of 5.29 and 17.60 μM, respectively, which were more active than their precursor leucosceptroid A.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d4cc03674c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Spatial distribution and driving factors of soil selenium on the Leizhou Peninsula, southern China.
Environ Geochem Health
January 2025
Institute of Geophysical and Geochemical Exploration, Chinese Academy of Geological Sciences, No. 84, Jinguang Road, Langfang, 065000, China.
Selenium (Se) is an essential element for humans, playing a critical role in the functioning of the immune system. The global prevalence of dietary Se deficiency is a significant public health concern, largely attributed to the low levels of Se present in crops. The sufficient Se in plants and humans is determined by the presence of stable Se sources in the soil.
View Article and Find Full Text PDFA Review of Current Developments in Functionalized Mesoporous Silica Nanoparticles: From Synthesis to Biosensing Applications.
Biosensors (Basel)
November 2024
School of Food Science and Engineering, Key Laboratory of Tropical Fruit and Vegetables Quality and Safety for State Market Regulation, Hainan University, Haikou 570228, China.
Functionalized mesoporous silica nanoparticles (MSNs) have been widely investigated in the fields of nanotechnology and material science, owing to their high surface area, diverse structure, controllable cavity, high biocompatibility, and ease of surface modification. In the past few years, great efforts have been devoted to preparing functionalized MSNs for biosensing applications with satisfactory performance. The functional structure and composition in the synthesis of MSNs play important roles in high biosensing performance.
View Article and Find Full Text PDFIn situ formed Se-TiO as a highly reusable photocatalyst for selenium reduction and removal from industrial wastewater.
Chemosphere
December 2024
Department of Chemical Engineering and Applied Chemistry, University of Toronto, 200 College St., Toronto, Ontario, M5S 3E5, Canada; Institute for Water Innovation, University of Toronto, 55 St. George St., Toronto, Ontario, M5S 1A4, Canada; Institute of Biomedical Engineering, University of Toronto, 164 College St., Toronto, Ontario, M5S 3G9, Canada. Electronic address:
Selenium (Se) release from anthropogenic activities such as mining, power generation, and agriculture poses considerable environmental and ecological risks. Increasing prevalence and awareness of Se-related issues have driven the development of many innovative Se treatment technologies. Photocatalysis has shown promise towards Se removal from industrial wastewaters with minimal residuals, and is generally considered a low-cost, robust, non-toxic, and potentially solar-powered method.
View Article and Find Full Text PDF(10)-4,5,6,7,8,9-Cyclo-deca-[][1,2,3]selena-diazole.
IUCrdata
November 2024
University of Mainz, Department of Chemistry, Duesbergweg 10-14, 55099 Mainz, Germany.
The title compound, CHNSe, was prepared from a semicarbazone and selenium dioxide. The planes of the heterocycle and the double bond are almost mutually orthogonal and the hexa-methyl-ene tether is nearly strain-free.
View Article and Find Full Text PDFResearch progress and application of carbon sequestration in industrial flue gas by microalgae: A review.
J Environ Sci (China)
June 2025
CAS Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Innovation Academy for Green Manufacture, Chinese Academy of Sciences, Beijing 100190, China; Center for Excellence in Regional Atmospheric Environment, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China. Electronic address:
Global warming caused by the emission of CO in industrial flue gas has attracted more and more attention. Therefore, to fix CO with high efficiency and environmentally friendly had become the hot research field. Compared with the traditional coal-fired power plant flue gas emission reduction technology, carbon fixation and emission reduction by microalgae is considered as a promising technology due to the advantages of simple process equipment, convenient operation and environmental protection.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!