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http://dx.doi.org/10.3389/fpls.2024.1460573 | DOI Listing |
J Thorac Oncol
January 2025
Department of Radiology, Center for Innovation in Imaging Biomarkers and Integrated Diagnostics (CIMBID), Columbia University, New York, New York; Department of Biomedical Informatics, Center for Innovation in Imaging Biomarkers and Integrated Diagnostics (CIMBID), Columbia University, New York, New York; Department of Biomedical Engineering, Center for Innovation in Imaging Biomarkers and Integrated Diagnostics (CIMBID), Columbia University, New York, New York.
Am J Ther
January 2025
Northwell, New Hyde Park, NY, Department of Medicine, Manhasset, NY.
Background: C3 glomerulopathy (C3G) is a rare disease affecting the complement alternative pathway, categorized into dense deposit disease and C3 glomerulonephritis. Dense deposit disease predominantly affects younger individuals, while C3 glomerulonephritis tends to manifest in older populations. The diseases are characterized by dysregulation of the complement alternative pathway, leading to the deposition of complement components in the glomeruli and subsequent renal dysfunction.
View Article and Find Full Text PDFAutophagy
January 2025
Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Lipophagy is a selective type of autophagy where lipid droplets are targeted to the lysosome/vacuole for degradation. Even though lipophagy has been reported in various species, many questions remain unaddressed. How are the lipid droplets sequestered to the lysosome? What is the lipophagy receptor? How is this receptor regulated at a posttranslational level? A new collaborative study among several universities conducted on mouse and human hepatocytes sheds light on these questions, deciphering the lipophagy mechanism in the liver.
View Article and Find Full Text PDFFront Cell Infect Microbiol
December 2024
Department of Dentistry, School of Health Sciences, University of Brasília, Brasilia, Brazil.
Front Genet
December 2024
Bioinformatics Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
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