AI Article Synopsis
- - The study investigates how laser speckle flowgraphy (LSFG) can assess changes in ocular blood flow after catheter ablation (CA) in patients with atrial fibrillation (AF).
- - Researchers monitored 28 AF patients (8 with paroxysmal AF and 20 with persistent AF) before and after CA, finding a significant increase in ocular blood flow in the persistent AF group, but no change in the paroxysmal group.
- - The findings suggest that successful heart rhythm restoration via CA can improve ocular blood circulation, indicating a potential link between heart health and eye/cognitive function.
Article Abstract
Aims: Laser speckle flowgraphy (LSFG) is a well-established tool renowned for its non-invasive and reproducible assessment of ocular blood flow. While rhythm control therapies, such as catheter ablation (CA), have shown promise in enhancing cognitive function in atrial fibrillation (AF) patients, the acute impact of CA on microcirculatory changes, particularly in ocular blood flow, remains a topic of limited understanding. The present study aims to delve into the potential of LSFG in detecting microcirculatory alterations following the restoration of sinus rhythm (SR) through CA in patients with AF.
Methods And Results: We studied 8 paroxysmal AF (Paf) and 20 persistent AF (PeAF) patients (mean age 67 ± 6 years, 26% female) undergoing CA. Ocular blood flow was assessed using LSFG by measuring the mean blur rate (MBR) pre- and post-CA. Post-CA, all PeAF patients achieved SR restoration, resulting in a significant increase in tissue MBR (10.0 ± 2.2 to 10.8 ± 2.9, = 0.021). In contrast, Paf patients showed no significant difference between pre- and post-MBR (12.0 ± 2.7 vs. 11.8 ± 2.6, = 0.76).
Conclusion: LSFG analysis effectively identified microcirculatory changes in patients undergoing CA for PeAF, suggesting that therapeutic interventions targeting the heart may have broader implications for ocular and cerebral health, establishing a novel 'cardio-oculo-cerebral relationship'.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11367941 | PMC |
| http://dx.doi.org/10.1093/ehjimp/qyae071 | DOI Listing |
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