Background: Inflammatory bowel disease (IBD) is a digestive system ailment that causes significant bodily disruption. This problem may coexist with other digestive system illnesses. One of the diseases that reduces the quality of life and other disorders is functional dyspepsia (FD), the diagnosis of which is associated with unique limitations. In this study, we aim to investigate the relative frequency of FD in IBD patients and compare it with a healthy control group.

Materials And Methods: In a case-control study, we selected a group of IBD patients and healthy controls, and all participants were prepared for a diagnosis of FD symptoms using ROME IV criteria. Data were analyzed and compared using Chi-square and -test, and ≤ 0.05 was considered significant.

Results: There were 100 IBD patients, including 91 with ulcerative colitis and 9 with Crohn's disease (mean age, 41.37 ± 13; 39 males, 61 females). Furthermore, 100 healthy control subjects (mean age, 44.23 ± 14; 38 males, 62 females) were analyzed. 10% of IBD patients met the criteria of FD, which was comparable with the controls (5, 5%) ( > 0.05). Some of the symptoms of irritable bowel syndrome (IBS) including abdominal pain ( = 0.01) and bowel movement = 0.02) were significantly higher in IBD patients than in non-IBD subjects.

Conclusions: The symptoms of FD were not significantly greater in IBD patients compared to the control group, while IBS symptoms were significantly higher in IBD individuals, indicating a possible overlap of Rome IV IBS and FD.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11368227PMC
http://dx.doi.org/10.4103/abr.abr_369_23DOI Listing

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