Hymenopteran insect stings are a risk factor that cannot be ignored for the people allergic to hymenopteran venoms.In China,the current diagnostic tools cannot provide accurate information to identify sensitized insects,thus affecting clinical diagnosis and treatment.Honeybee is a common hymenopteran insect.Due to its wide distribution,large number,and complex venom composition,researchers have carried out recombination schemes for the main allergens of honeybee venom,laying a theoretical foundation for the detection of allergens.The development of diagnostic technologies for allergen components can accurately detect bee venom allergens,providing a new set of clinical diagnosis and treatment schemes for the population allergic to bee venom.
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http://dx.doi.org/10.3881/j.issn.1000-503X.15770 | DOI Listing |
Med Oncol
December 2024
Department of Medical Biology, Faculty of Medicine, Ordu University, Ordu, Turkey.
Thyroid cancer continues to be a notable health issue, requiring the creation of novel treatment methods to enhance patient results. The objective of this study is to investigate the potential of utilizing bee venom (BV)-loaded zeolitic imidazolate framework-8 (ZIF-8) nanoparticles as a novel strategy for specifically targeting and treating medullary thyroid cancer cells. Due to their wide surface area and configurable pore size, ZIF-8 nanoparticles are ideal for drug delivery.
View Article and Find Full Text PDFBraz J Biol
December 2024
AL-Balqa Applied University, Faculty of Agricultural Technology, Department of Plant Production and Protection, Al-Salt, Jordan.
Ethanolic extracts of seasonally collected natural bee products (honey, propolis, royal jelly (RJ), and bee venom (BV)) were tested for their potential as antimicrobial agents against antibiotic-resistant bacteria and fungi. These extracts exhibited various inhibitory effects on antibiotic-resistant bacteria (Streptococcus pneumoniae, Staphylococcus aureus, MRSA, Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus vulgaris, and Haemophilus influenzae) and fungi (Aspergillus brasiliensis and Candida albicans), with the exception of S. pneumonia, which was not inhibited by honey and RJ extracts, and P.
View Article and Find Full Text PDFOnderstepoort J Vet Res
December 2024
Department of Parasitology, Ceyhan Veterinary Faculty, Cukurova University, Adana, Türkiye; and Department of Biotechnology, Institute of Natural and Applied Sciences, Cukurova University, Adana.
Natural treatment options for Microsporum canis dermatophytosis are being explored because of resistance to several antifungal medications. In this study, the potential antifungal effect of bee venom (BV), a natural antimicrobial agent, on M. canis was investigated.
View Article and Find Full Text PDFFront Immunol
November 2024
Immunochemistry Laboratory, Butantan Institute, São Paulo, Brazil.
Chin Med
November 2024
College of Korean Medicine, Dongshin University, Naju, 58245, Republic of Korea.
The Nuclear factor erythroid 2-related factor (Nrf2)/ Heme oxygenase-1 (HO-1) pathway, known for its significant role in regulating innate antioxidant defense mechanisms, is increasingly being recognized for its potential in neuroprotection studies. Derived from bee venom, melittin's neuroprotective effects have raised interest. This study confirmed that melittin specificity upregulated the weakened Nrf2/HO-1 signaling in mice brain.
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