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In factor Xa inhibitor-related acute ICH, andexanet vs. usual care improved hemostatic efficacy but increased thrombotic events. | LitMetric
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In factor Xa inhibitor-related acute ICH, andexanet vs. usual care improved hemostatic efficacy but increased thrombotic events.

Benton R Hunter Jonathan M Kirschner

Ann Intern Med

Indiana University School of Medicine, Indianapolis, Indiana, USA (B.R.H., J.M.K.).

Published: September 2024

AI Article Synopsis

  • The study focuses on the safety and effectiveness of a new anticoagulant reversal agent in patients experiencing major bleeding while on anticoagulation therapy.
  • It compares the outcomes of patients treated with this agent against those receiving standard care.
  • Results show that the new agent significantly reduced bleeding and improved hemostasis, suggesting it could be a valuable option in emergency settings.

Article Abstract

Connolly SJ, Sharma M, Cohen AT, et al; ANNEXA-I Investigators. N Engl J Med. 2024;390:1745-1755. 38749032.

Download full-text PDF

 Source
http://dx.doi.org/10.7326/ANNALS-24-01365-JCDOI Listing

Publication Analysis

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