Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/15563650.2024.2389306 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Obesity-induced activation of NADPH oxidase 2 prolongs cardiac repolarization via inhibiting K+ currents.
PLoS One
December 2024
Chinese PLA Medical School, Chinese PLA General Hospital, Beijing, China.
Obesity is associated with abnormal repolarization manifested by QT interval prolongation, and oxidative stress is an important link between obesity and arrhythmias. However, the underlying electrophysiological and molecular mechanisms remain unclear. The aim of this study is to evaluate the role of obesity in potassium current in ventricular myocytes and the potential mechanism of NADPH oxidase 2 (Nox2).
View Article and Find Full Text PDFK currents in ventricular cardiomyocytes of p.N98S-calmodulin mutant mice.
Am J Physiol Heart Circ Physiol
December 2024
Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
Missense mutations in calmodulin (CaM)-encoding genes are associated with life-threatening ventricular arrhythmia syndromes. Here, we investigated a role of cardiac K channel dysregulation in arrhythmogenic long QT syndrome (LQTS) using a knock-in mouse model heterozygous for a recurrent mutation (p.N98S) in the gene (Calm1).
View Article and Find Full Text PDFDiagnostic delay, older age, and hormonal levels at diagnosis affect disease burden and mortality in acromegaly.
J Endocrinol Invest
December 2024
Division of Endocrinology, Diabetes, and Metabolism, Department of Medical Science, University of Turin, Turin, Italy.
Purpose: Acromegaly, a rare disease with peak incidence in early adulthood, is marked by significant diagnostic delay and increased mortality due to complications. While older patients often show milder disease activity, they experience longer diagnostic delay. Higher hormonal levels, advanced age, and prolonged delay are associated with more systemic complications.
View Article and Find Full Text PDFLong-term data reveal widespread phenological change across major US estuarine food webs.
Ecol Lett
December 2024
Department of Environmental Science, Policy, and Management, University of California Berkeley, Berkeley, California, USA.
Climate change is shifting the timing of organismal life-history events. Although consequential food-web mismatches can emerge if predators and prey shift at different rates, research on phenological shifts has traditionally focused on single trophic levels. Here, we analysed >2000 long-term, monthly time series of phytoplankton, zooplankton, and fish abundance or biomass for the San Francisco, Chesapeake, and Massachusetts bays.
View Article and Find Full Text PDFDesign and implementation of the fractional-order controllers for a real-time nonlinear process using the AGTM optimization technique.
Sci Rep
December 2024
School of Electrical Engineering, Vellore Institute of Technology, Chennai, 600127, India.
Spherical tanks have been predominantly used in process industries due to their large storage capability. The fundamental challenges in process industries require a very efficient controller to control the various process parameters owing to their nonlinear behavior. The current research work in this paper aims to propose the Approximate Generalized Time Moments (AGTM) optimization technique for designing Fractional-Order PI (FOPI) and Fractional-Order PID (FOPID) controllers for the nonlinear Single Spherical Tank Liquid Level System (SSTLLS).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!